Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3516411 | 0.90 | ALK (0.41) | AURKAMAPK14MMP2FEN1 | |
| SCHEMBL3518140 | 0.85 | FEN1 (0.44) | AURKAMAPK14KDM4ETP53MAPT | |
| SCHEMBL3514751 | 0.81 | SIRT2 (0.45) | MAPK14FEN1HDAC6 | |
| SCHEMBL3515039 | 0.76 | FABP3 (0.43) | AURKAKDM4EALOX15HSD17B10FEN1 | |
| SCHEMBL18136095 | 0.75 | FEN1 (0.47) | KDM4EHPGDFEN1 | |
| SCHEMBL3514404 | 0.74 | CYP3A4 (0.38) | KDM4EL3MBTL1FEN1 | |
| SCHEMBL3516135 | 0.73 | FEN1 (0.46) | KDM4EMAPTHPGDBLMFEN1 | |
| SCHEMBL3514825 | 0.73 | IDH1 (0.41) | FEN1 | |
| SCHEMBL3519112 | 0.72 | MEN1 (0.54) | TP53HPGDALOX15FEN1 | |
| SCHEMBL2020155 | 0.70 | ABCG2 (0.49) | TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240368637-A1 | METHODS AND MICROORGANISMS FOR MAKING 1,4-BUTANEDIOL AND DERIVATIVES THEREOF FROM C1 CARBONS | PRECIGEN, INC. (US) | 2024-11-07 | — | — | US | disclosed |
| US-12018310-B2 | Methods and microorganisms for making 1,4-butanediol and derivatives thereof from C1 carbons | PRECIGEN, INC. (US) | 2024-06-25 | — | — | US | disclosed |
| US-20220064677-A1 | METHODS AND MICROORGANISMS FOR MAKING 1,4-BUTANEDIOL AND DERIVATIVES THEREOF FROM C1 CARBONS | PRECIGEN, INC. (US) | 2022-03-03 | — | — | US | disclosed |