SCHEMBL29587296

SCHEMBL29587296

O=C(O)CCNC(=O)CNC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.69

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.68
EPHX2 P34913 1/20 0.47
CASP3 P42574 2/20 0.45
OPRD1 P41143 1/20 0.45
FABP7 O15540 2/20 0.43
FABP5 Q01469 2/20 0.43
CXCR2 P25025 1/20 0.43
MDM4 O15151 1/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18429473 1.00 KMT2A (0.68) KMT2AEPHX2CASP3OPRD1FABP7
SCHEMBL17177621 0.93 KMT2A (0.76) KMT2AEPHX2CASP3OPRD1FABP7
SCHEMBL29485093 0.92 KMT2A (0.74) KMT2AEPHX2CASP3OPRD1FABP7
SCHEMBL13525077 0.91 KMT2A (0.73) KMT2AEPHX2CASP3FABP7FABP5
SCHEMBL3140809 0.91 KMT2A (0.73) KMT2AEPHX2CASP3FABP7FABP5
SCHEMBL178687 0.91 KMT2A (0.81) KMT2AEPHX2CASP3OPRD1FABP7
SCHEMBL29397906 0.91 KMT2A (0.81) KMT2AEPHX2CASP3OPRD1FABP7
SCHEMBL29423575 0.91 KMT2A (0.81) KMT2AEPHX2CASP3OPRD1FABP7
SCHEMBL8654488 0.91 KMT2A (0.84) KMT2AEPHX2CASP3OPRD1
SCHEMBL29975343 0.89 KMT2A (0.60) KMT2AEPHX2CASP3OPRD1FABP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12379357-B2 Method for quantifying amino group-containing compound protected by protecting group having Fmoc skeleton CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-08-05 US disclosed
CN-114585916-B Method for quantifying compound containing amino group protected with protecting group having Fmoc skeleton 中外制药株式会社 2025-03-11 CN disclosed
US-20240151696-A1 METHOD FOR QUANTIFYING AMINO GROUP-CONTAINING COMPOUND PROTECTED BY PROTECTING GROUP HAVING FMOC SKELETON CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-05-09 US disclosed
US-20230295221-A1 EFFICIENT PEPTIDE CONDENSATION METHOD FOR DIFFICULT SEQUENCES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-09-21 US disclosed
EP-4144747-A1 EFFICIENT PEPTIDE CONDENSATION METHOD FOR DIFFICULT SEQUENCES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-03-08 EP disclosed
CN-115698032-A Efficient peptide condensation of difficult sequences 中外制药株式会社 2023-02-03 CN disclosed
EP-4046982-A1 METHOD FOR QUANTIFYING AMINO GROUP-CONTAINING COMPOUND PROTECTED BY PROTECTING GROUP HAVING FMOC SKELETON CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2022-08-24 EP disclosed
CN-114585916-A Method for quantifying compound having amino group protected with protecting group having Fmoc skeleton 中外制药株式会社 2022-06-03 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230295221-A1 EFFICIENT PEPTIDE CONDENSATION METHOD FOR DIFFICULT SEQUENCES NGLY1, VIP, DNPEP KMT2A 3727/4885EPHX2 3850/4885CASP3 4334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.