SCHEMBL178687

SCHEMBL178687

O=C(O)CCNC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.81

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.81
EPHX2 P34913 1/20 0.52
CASP3 P42574 2/20 0.49
FABP5 Q01469 3/20 0.48
FABP7 O15540 2/20 0.48
HTT P42858 1/20 0.47
MDM4 O15151 1/20 0.44
TP53 P04637 1/20 0.44
OPRD1 P41143 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29397906 1.00 KMT2A (0.81) KMT2AEPHX2CASP3FABP5FABP7
SCHEMBL29423575 1.00 KMT2A (0.81) KMT2AEPHX2CASP3FABP5FABP7
SCHEMBL13525077 0.95 KMT2A (0.73) KMT2AEPHX2CASP3FABP5FABP7
SCHEMBL3140809 0.95 KMT2A (0.73) KMT2AEPHX2CASP3FABP5FABP7
SCHEMBL29792075 0.92 KMT2A (0.90) KMT2AEPHX2CASP3FABP5FABP7
SCHEMBL29370234 0.92 KMT2A (0.90) KMT2AEPHX2CASP3FABP5FABP7
SCHEMBL178801 0.92 KMT2A (0.90) KMT2AEPHX2CASP3FABP5FABP7
SCHEMBL18429473 0.91 KMT2A (0.68) KMT2AEPHX2CASP3FABP5FABP7
SCHEMBL29587296 0.91 KMT2A (0.68) KMT2AEPHX2CASP3FABP5FABP7
Water SCHEMBL21809392 0.91 KMT2A (0.88) KMT2AEPHX2CASP3FABP5FABP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 715 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119874813-A Short peptide compound and preparation method thereof, cosmetic composition and application 常州市智态生创科技有限公司 2025-04-25 CN claimed
CN-119859167-A Preparation method of ISARIDIN E cyclic ester peptide 中山大学 2025-04-22 CN claimed
CN-119529014-A Tripterine-platinum (IV) complex with antitumor activity and preparation method and application thereof 河北大学 2025-02-28 CN claimed
CN-115521362-B Preparation method of Pseudodestruxin B 哈尔滨工业大学(深圳) 2024-05-28 CN claimed
CN-117285592-A Preparation method of cyclohexalipopeptides natural product Cladoamide B 哈尔滨工业大学(深圳) 2023-12-26 CN claimed
CN-117285602-A Preparation method of depsipeptide natural product Isaridin A 哈尔滨工业大学(深圳) 2023-12-26 CN claimed
CN-115626951-A CladoamideA preparation method 哈尔滨工业大学(深圳) 2023-01-20 CN claimed
CN-115521358-A Preparation method of destruxins B 哈尔滨工业大学(深圳) 2022-12-27 CN claimed
CN-115521362-A Preparation method of pseudodestruxinB 哈尔滨工业大学(深圳) 2022-12-27 CN claimed
CN-112694429-B Polypeptide and application thereof in preparing ACE inhibitor or blood pressure lowering product 江苏医药职业学院 2022-08-19 CN claimed
EP-3988538-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF Zhejiang Zhida Pharmaceutical Co., Ltd. (CN) 2022-04-27 EP claimed
CN-113999141-A Synthesis method of N-Fmoc-3-aminopropionic acid derivative 苏州爱玛特生物科技有限公司 2022-02-01 CN claimed
CN-112694429-A Polypeptide and application thereof in preparing ACE inhibitor or blood pressure lowering product 江苏医药职业学院 2021-04-23 CN claimed
WO-2020252713-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF 浙江智达药业有限公司 2020-12-24 WO claimed
CN-112110834-A Modified hydrophobic auxiliary material and preparation method and application thereof 浙江智达药业有限公司 2020-12-22 CN claimed
CN-111747967-A Dihydroartemisinin/neurotransmitter split compound and its synthesis method and use 广州药本君安医药科技股份有限公司 2020-10-09 CN claimed
EP-0357750-B1 URETHANE-PROTECTED AMINO ACID-N-CARBOXYANHYDRIDES BIORESEARCH INC (US) 1994-07-13 EP claimed
US-20260139075-A1 NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF ROCHE DIAGNOSTICS OPERATIONS INC (US) 2026-05-21 US disclosed
WO-1989009625-A1 CONTRAST AGENTS FOR MAGNETIC RESONANCE IMAGING COCKBAIN, JULIAN, RODERICK, MICHAELSON (GB) 1989-10-19 WO disclosed
EP-0312360-A2 25-Hydroxy vitamin D3 derivatives TOYO JOZO KABUSHIKI KAISHA (JP) 1989-04-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260139075-A1 NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF CD22, LY96, F13B KMT2A 1552/4885EPHX2 2192/4885CASP3 4484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.