Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.84 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5532293 | 1.00 | LMNA (0.84) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| Chlorothymol SCHEMBL159122 | 0.91 | LMNA (1.00) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| Chlorothymol SCHEMBL29431017 | 0.91 | LMNA (1.00) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL10702604 | 0.84 | LMNA (0.72) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL25552477 | 0.81 | LMNA (0.68) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL214157 | 0.81 | LMNA (0.68) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL29872559 | 0.81 | LMNA (0.68) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL12297358 | 0.79 | LMNA (0.59) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL9556365 | 0.79 | LMNA (0.65) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL10013261 | 0.79 | LMNA (0.59) | LMNATRPA1CHRM1SLC6A2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11352330-B2 | Phenoxymethyl derivatives | HOFFMANN-LA ROCHE INC. (US) | 2022-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11352330-B2 | Phenoxymethyl derivatives | CNKSR1, RB1, RCOR1 | LMNA 2843/4885TRPA1 3835/4885CHRM1 1442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.