Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.59 |
| ▸ | PIM1 | P11309 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GNE | Q9Y223 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine Dicarboxamide SCHEMBL229425 | 1.00 | TSHR (0.59) | TSHRTDP1KDM4EALOX15ACMSD | |
| Pyridine Dicarboxamide SCHEMBL29031925 | 0.97 | TSHR (0.56) | TSHRTDP1KDM4EALOX15ACMSD | |
| Pyridine Dicarboxamide SCHEMBL29501171 | 0.97 | TSHR (0.56) | TSHRTDP1KDM4EALOX15ACMSD | |
| Pyridine Dicarboxamide SCHEMBL15347496 | 0.97 | TSHR (0.56) | TSHRTDP1KDM4EALOX15ACMSD | |
| Pyridine Dicarboxamide SCHEMBL38659131 | 0.97 | TSHR (0.56) | TSHRTDP1KDM4EALOX15ACMSD | |
| SCHEMBL1244359 | 0.91 | KDM4E (0.77) | TSHRTDP1KDM4EALOX15ACMSD | |
| SCHEMBL9298315 | 0.89 | KDM4E (0.48) | TSHRTDP1KDM4EALOX15ACMSD | |
| SCHEMBL9792961 | 0.87 | PIM1 (0.50) | TSHRTDP1KDM4EALOX15ACMSD | |
| SCHEMBL29447032 | 0.85 | PIM1 (0.53) | TSHRTDP1KDM4EALOX15ACMSD | |
| SCHEMBL3285205 | 0.85 | PIM1 (0.53) | TSHRTDP1KDM4EALOX15ACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478584-A | Rhodamine B-based Cu2+Fluorescent sensor and preparation method thereof | 南京理工大学 | 2022-05-13 | — | — | CN | disclosed |