SCHEMBL1244359

SCHEMBL1244359

NC(=O)c1cccc(C(=O)O)n1

nearest known ligand 0.77

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.77
ALOX15 P16050 1/20 0.77
TSHR P16473 1/20 0.77
ACMSD Q8TDX5 1/20 0.77
TDP1 Q9NUW8 1/20 0.77
GNE Q9Y223 1/20 0.56
LMNA P02545 2/20 0.48
PIM1 P11309 1/20 0.48
CA1 P00915 4/20 0.46
CA2 P00918 4/20 0.46
KMT2A Q03164 1/20 0.46
MGAM O43451 1/20 0.45
NAPRT Q6XQN6 1/20 0.45
P4HTM Q9NXG6 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine Dicarboxamide SCHEMBL29587789 0.91 TSHR (0.59) KDM4EALOX15TSHRACMSDTDP1
Pyridine Dicarboxamide SCHEMBL229425 0.91 TSHR (0.59) KDM4EALOX15TSHRACMSDTDP1
Pyridine Dicarboxamide SCHEMBL29501171 0.88 TSHR (0.56) KDM4EALOX15TSHRACMSDTDP1
Pyridine Dicarboxamide SCHEMBL29031925 0.88 TSHR (0.56) KDM4EALOX15TSHRACMSDTDP1
Pyridine Dicarboxamide SCHEMBL15347496 0.88 TSHR (0.56) KDM4EALOX15TSHRACMSDTDP1
Pyridine Dicarboxamide SCHEMBL38659131 0.88 TSHR (0.56) KDM4EALOX15TSHRACMSDTDP1
Dipicolinic Acid SCHEMBL720696 0.88 KDM4E (1.00) KDM4EALOX15TSHRACMSDTDP1
Dipicolinic Acid SCHEMBL34595 0.88 KDM4E (1.00) KDM4EALOX15TSHRACMSDTDP1
Dipicolinic Acid SCHEMBL3732330 0.85 KDM4E (0.94) KDM4EALOX15TSHRACMSDTDP1
Dipicolinic Acid SCHEMBL9491853 0.85 KDM4E (0.94) KDM4EALOX15TSHRACMSDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117362628-A Perfluoro polyether type conductive agent and preparation method and application thereof 中国石油化工股份有限公司 2024-01-09 CN claimed
EP-1125498-B1 Spore germination inhibitor and food using the same AJINOMOTO KK (JP) 2004-08-25 EP claimed
US-6506431-B2 Using 6-carbamoyl-2-pyridine carboxylic acid AJINOMOTO CO., INC. (JP) 2003-01-14 US claimed
US-20010019720-A1 Spore germination inhibitor and food using the same AJINOMOTO CO., INC. (JP) 2001-09-06 US claimed
EP-1125498-A2 Spore germination inhibitor and food using the same Ajinomoto Co., Inc. (JP) 2001-08-22 EP claimed
WO-2024222837-A1 TETRAHYDRONAPHTHYLPROPYLAMINOMETHYLPIPERIDINE ARYL (SULFONYL)AMIDE DERIVATIVE, PREPARATION METHOD, AND APPLICATION THEREOF 江苏恩华药业股份有限公司 2024-10-31 WO disclosed
CN-117362628-A Perfluoro polyether type conductive agent and preparation method and application thereof 中国石油化工股份有限公司 2024-01-09 CN disclosed
US-20230143425-A1 IMPROVEMENTS RELATED TO SORBENT MEDIA GENESIS SYSTEMS LLC 2023-05-11 US disclosed
EP-3212637-B1 DOPAMINE D3 RECEPTOR ANTAGONISTS COMPOUNDS INDIVIOR UK LTD (GB) 2021-06-02 EP disclosed
EP-3212637-B1 DOPAMINE D3 RECEPTOR ANTAGONISTS COMPOUNDS INDIVIOR UK LTD (GB) 2021-06-02 EP disclosed
US-10654842-B2 Dopamine D3 receptor antagonist compounds INDIVIOR UK LIMITED (GB) 2020-05-19 US disclosed
US-10654842-B2 Dopamine D3 receptor antagonist compounds INDIVIOR UK LIMITED (GB) 2020-05-19 US disclosed
US-6506431-B2 Using 6-carbamoyl-2-pyridine carboxylic acid AJINOMOTO CO., INC. (JP) 2003-01-14 US disclosed
US-6506431-B2 Using 6-carbamoyl-2-pyridine carboxylic acid AJINOMOTO CO., INC. (JP) 2003-01-14 US disclosed
EP-1125498-A3 Spore germination inhibitor and food using the same Ajinomoto Co., Inc. (JP) 2002-08-14 EP disclosed
JP-2001302417-A SPORE GERMINATION INHIBITOR AND FOOD USING THE SAME AJINOMOTO CO INC 2001-10-31 JP disclosed
US-20010019720-A1 Spore germination inhibitor and food using the same AJINOMOTO CO., INC. (JP) 2001-09-06 US disclosed
US-20010019720-A1 Spore germination inhibitor and food using the same AJINOMOTO CO., INC. (JP) 2001-09-06 US disclosed
EP-1125498-A2 Spore germination inhibitor and food using the same Ajinomoto Co., Inc. (JP) 2001-08-22 EP disclosed
EP-1125498-A2 Spore germination inhibitor and food using the same Ajinomoto Co., Inc. (JP) 2001-08-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010019720-A1 Spore germination inhibitor and food using the same DDC, DAO, AADAT KDM4E 385/4885ALOX15 2876/4885TSHR 4815/4885
US-10654842-B2 Dopamine D3 receptor antagonist compounds DRD3, DRD2, DRD4 KDM4E 3324/4885ALOX15 3716/4885TSHR 148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.