Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 20/20 | 0.56 |
| ▸ | BCL2 | P10415 | 17/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 11/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29588224 | 0.92 | BCL2L1 (0.53) | BCL2L1BCL2MCL1 | |
| SCHEMBL30528147 | 0.88 | BCL2L1 (0.62) | BCL2L1BCL2MCL1 | |
| SCHEMBL30112782 | 0.85 | ALDH3A1 (0.50) | BCL2L1BCL2MCL1 | |
| SCHEMBL29588200 | 0.85 | BCL2L1 (0.53) | BCL2L1BCL2MCL1 | |
| SCHEMBL30921530 | 0.83 | BCL2L1 (0.43) | BCL2L1BCL2MCL1 | |
| SCHEMBL29589481 | 0.83 | BCL2 (0.47) | BCL2L1BCL2 | |
| SCHEMBL30421841 | 0.81 | BCL2L1 (0.52) | BCL2L1BCL2MCL1 | |
| SCHEMBL30112860 | 0.81 | BCL2L1 (0.52) | BCL2L1BCL2MCL1 | |
| SCHEMBL30365352 | 0.80 | BCL2L1 (0.56) | BCL2L1BCL2MCL1 | |
| SCHEMBL30112854 | 0.80 | HRH1 (0.46) | BCL2L1BCL2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478520-B | Bcl-2 protein apoptosis inducer and application thereof | 杭州和正医药有限公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-114478520-A | Bcl-2 protein apoptosis inducer and application thereof | 杭州和正医药有限公司 | 2022-05-13 | — | — | CN | disclosed |