Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 9/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29588140 | 0.85 | CYP2C19 (0.35) | CYP2C19HTR6DRD2HTR2AMET | |
| SCHEMBL27436471 | 0.76 | CYP2C19 (0.46) | CYP2C19HTR6DRD2HTR2AMET | |
| SCHEMBL28735157 | 0.73 | CYP2C19 (0.38) | CYP2C19HTR6DRD2HTR2AMET | |
| SCHEMBL29587533 | 0.73 | CYP2C19 (0.38) | CYP2C19HTR6DRD2HTR2AMET | |
| SCHEMBL29587820 | 0.73 | HTR2B (0.32) | CYP2C19HTR6DRD2HTR2ABRD4 | |
| SCHEMBL25696582 | 0.73 | CYP2C19 (0.45) | CYP2C19HTR6DRD2HTR2AMET | |
| SCHEMBL27434345 | 0.71 | CYP2C19 (0.43) | CYP2C19HTR6DRD2HTR2AMET | |
| SCHEMBL20289951 | 0.71 | CYP2C19 (0.43) | CYP2C19HTR6DRD2HTR2AMET | |
| SCHEMBL2279091 | 0.71 | CYP2C19 (0.34) | CYP2C19HTR6DRD2HTR2ABRD4 | |
| SCHEMBL2225345 | 0.71 | HTR6 (0.38) | CYP2C19HTR6DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478528-A | Aroyl-substituted tricyclic compound, preparation method and application thereof | 劲方医药科技(上海)有限公司 | 2022-05-13 | — | — | CN | disclosed |