Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.89 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | NME2 | P22392 | 4/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 6/20 | 0.48 |
| ▸ | TUBB | P07437 | 6/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 6/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 6/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 6/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 6/20 | 0.48 |
| ▸ | TUBB6 | Q9BUF5 | 6/20 | 0.48 |
| ▸ | TUBB2B | Q9BVA1 | 6/20 | 0.48 |
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30775597 | 0.94 | KDR (1.00) | KDRALOX5RAB9ANPC1NME2 | |
| SCHEMBL29019790 | 0.94 | KDR (1.00) | KDRALOX5RAB9ANPC1NME2 | |
| SCHEMBL30775598 | 0.85 | KDR (0.84) | KDRALOX5RAB9ANPC1NME2 | |
| SCHEMBL29140308 | 0.85 | KDR (0.84) | KDRALOX5RAB9ANPC1NME2 | |
| SCHEMBL29589519 | 0.85 | KDR (0.66) | KDRALOX5RAB9ANPC1NME2 | |
| SCHEMBL29589513 | 0.83 | KDR (0.63) | KDRALOX5RAB9ANPC1NME2 | |
| SCHEMBL29140340 | 0.83 | KDR (0.79) | KDRALOX5RAB9ANPC1NME2 | |
| SCHEMBL30775600 | 0.82 | KDR (0.79) | KDRALOX5RAB9ANPC1NME2 | |
| SCHEMBL29589238 | 0.81 | KDR (0.59) | KDRALOX5RAB9ANPC1MEN1 | |
| SCHEMBL29589174 | 0.81 | KDR (0.59) | KDRALOX5RAB9ANPC1NME2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478549-B | Pyrazolo [3,4-d ] pyrrolo [1,2-a ] pyrimidinone arylene derivative and application thereof | 中国科学院新疆理化技术研究所 | 2023-06-23 | — | — | CN | claimed |
| CN-114478549-A | Pyrazolo [3,4-d ] pyrrolo [1,2-a ] pyrimidone arylene derivative and application thereof | 中国科学院新疆理化技术研究所 | 2022-05-13 | — | — | CN | claimed |
| CN-114478549-B | Pyrazolo [3,4-d ] pyrrolo [1,2-a ] pyrimidinone arylene derivative and application thereof | 中国科学院新疆理化技术研究所 | 2023-06-23 | — | — | CN | disclosed |
| CN-114478549-A | Pyrazolo [3,4-d ] pyrrolo [1,2-a ] pyrimidone arylene derivative and application thereof | 中国科学院新疆理化技术研究所 | 2022-05-13 | — | — | CN | disclosed |