Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.37 |
| ▸ | MDK | P21741 | 4/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | PADI6 | Q6TGC4 | 1/20 | 0.34 |
| ▸ | COMT | P21964 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.34 |
| ▸ | CASP3 | P42574 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP2 | P42575 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16085110 | 0.96 | F2 (0.48) | F2SETD7MDKPLGPRSS1 | |
| SCHEMBL13551195 | 0.91 | F2 (0.57) | F2PLG | |
| SCHEMBL4732589 | 0.87 | F2 (0.42) | F2SETD7MDKPSEN1PSEN2 | |
| SCHEMBL12458605 | 0.87 | F2 (0.45) | F2SETD7MDKPLGPRSS1 | |
| SCHEMBL12799348 | 0.87 | F2 (0.45) | F2SETD7MDKPLGPRSS1 | |
| SCHEMBL12799315 | 0.87 | F2 (0.45) | F2SETD7MDKPLGPRSS1 | |
| SCHEMBL12458597 | 0.85 | F2 (0.43) | F2SETD7MDKPLGPRSS1 | |
| SCHEMBL12458604 | 0.84 | F2 (0.42) | F2SETD7MDKPSEN1PSEN2 | |
| SCHEMBL12458591 | 0.84 | F2 (0.42) | F2SETD7MDKPSEN1PSEN2 | |
| SCHEMBL14959577 | 0.83 | F2 (0.48) | F2PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12454520-B2 | Protein degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2025-10-28 | — | — | US | disclosed |
| US-20250214969-A1 | PROTEIN DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2025-07-03 | — | — | US | disclosed |
| US-20250114499-A1 | BIOTIN-AVIDIN CONTROLLED DELIVERY SYSTEMS | UNIV DREXEL (US) | 2025-04-10 | — | — | US | disclosed |
| US-12006329-B2 | Protein degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2024-06-11 | — | — | US | disclosed |
| US-11623932-B2 | Protein degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2023-04-11 | — | — | US | disclosed |
| EP-4119131-A1 | DRY POWDER FORMULATIONS FOR INHALATION | Otitopic Inc. (US) | 2023-01-18 | — | — | EP | disclosed |
| US-20220202994-A1 | BIOTIN-AVIDIN CONTROLLED DELIVERY SYSTEMS | DREXEL UNIVERSITY | 2022-06-30 | — | — | US | disclosed |
| EP-3107548-B1 | DRY POWDER FORMULATIONS FOR INHALATION | OTITOPIC INC (US) | 2022-06-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12006329-B2 | Protein degraders and uses thereof | MDM2, CUL1, PSMG3 | F2 4092/4885SETD7 1910/4885MDK 3592/4885 |
| US-12454520-B2 | Protein degraders and uses thereof | MDM2, CUL1, PSMG3 | F2 4092/4885SETD7 1910/4885MDK 3592/4885 |
| US-11623932-B2 | Protein degraders and uses thereof | MDM2, CUL1, PSMG3 | F2 4092/4885SETD7 1910/4885MDK 3592/4885 |
| US-20250214969-A1 | PROTEIN DEGRADERS AND USES THEREOF | MDM2, CUL1, PSMG3 | F2 4092/4885SETD7 1910/4885MDK 3592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.