Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 2/20 | 0.60 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RAF1 | P04049 | 6/20 | 0.46 |
| ▸ | BRAF | P15056 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14785990 | 1.00 | KCNQ3 (0.60) | KCNQ3KCNQ2MAPTLMNAMAPK1 | |
| SCHEMBL14785867 | 0.92 | KCNQ3 (0.51) | KCNQ3KCNQ2MAPTLMNAMAPK1 | |
| SCHEMBL14783768 | 0.92 | KCNQ3 (0.51) | KCNQ3KCNQ2MAPTLMNAMAPK1 | |
| SCHEMBL29590325 | 0.92 | KCNQ3 (0.51) | KCNQ3KCNQ2MAPTLMNAMAPK1 | |
| SCHEMBL29590147 | 0.92 | KCNQ3 (0.51) | KCNQ3KCNQ2MAPTLMNAMAPK1 | |
| SCHEMBL29591012 | 0.92 | MAPT (0.54) | KCNQ3KCNQ2MAPTLMNAMAPK1 | |
| SCHEMBL14783332 | 0.92 | MAPT (0.54) | KCNQ3KCNQ2MAPTLMNAMAPK1 | |
| SCHEMBL29591611 | 0.91 | RAB9A (0.52) | KCNQ3KCNQ2MAPTLMNAMAPK1 | |
| SCHEMBL14786126 | 0.91 | RAB9A (0.52) | KCNQ3KCNQ2MAPTLMNAMAPK1 | |
| SCHEMBL14785849 | 0.90 | KCNQ3 (0.59) | KCNQ3KCNQ2MAPTLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403531-A | Chemical entities, compositions, and methods as kinase inhibitors | 润新生物公司 | 2022-11-29 | — | — | CN | disclosed |
| CN-108794411-B | Certain chemical entities, compositions, and methods | 润新生物公司 | 2022-06-07 | — | — | CN | disclosed |