Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 11/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | FPR1 | P21462 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14783088 | 1.00 | EPHX2 (0.57) | EPHX2MAPTSTAT3SMN1; SMN2MCHR1 | |
| SCHEMBL29590204 | 0.93 | RAF1 (0.49) | EPHX2MAPTSTAT3SMN1; SMN2BRAF | |
| SCHEMBL14783483 | 0.93 | RAF1 (0.49) | EPHX2MAPTSTAT3SMN1; SMN2BRAF | |
| SCHEMBL29590933 | 0.92 | AKT1 (0.49) | EPHX2MAPTSTAT3SMN1; SMN2MCHR1 | |
| SCHEMBL14783387 | 0.92 | AKT1 (0.49) | EPHX2MAPTSTAT3SMN1; SMN2MCHR1 | |
| SCHEMBL14784050 | 0.92 | MTOR (0.51) | EPHX2MAPTMTORKCNQ3KCNQ2 | |
| SCHEMBL29590344 | 0.92 | MTOR (0.51) | EPHX2MAPTMTORKCNQ3KCNQ2 | |
| SCHEMBL14783836 | 0.91 | EPHX2 (0.45) | EPHX2MAPTSTAT3SMN1; SMN2MCHR1 | |
| SCHEMBL29591695 | 0.91 | EPHX2 (0.45) | EPHX2MAPTSTAT3SMN1; SMN2MCHR1 | |
| SCHEMBL29591439 | 0.91 | MTOR (0.51) | EPHX2MAPTSMN1; SMN2MCHR1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403531-A | Chemical entities, compositions, and methods as kinase inhibitors | 润新生物公司 | 2022-11-29 | — | — | CN | disclosed |
| CN-108794411-B | Certain chemical entities, compositions, and methods | 润新生物公司 | 2022-06-07 | — | — | CN | disclosed |