Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | BRAF | P15056 | 10/20 | 0.50 |
| ▸ | RAF1 | P04049 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | APAF1 | O14727 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.48 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.48 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.48 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.48 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14783762 | 1.00 | MAPT (0.54) | MAPTBRAFRAF1MEN1KMT2A | |
| SCHEMBL14782951 | 0.92 | BRAF (0.59) | BRAFRAF1KDM4E | |
| SCHEMBL29590391 | 0.92 | MEN1 (0.47) | MAPTBRAFRAF1MEN1KMT2A | |
| SCHEMBL14783172 | 0.92 | MEN1 (0.47) | MAPTBRAFRAF1MEN1KMT2A | |
| SCHEMBL14783338 | 0.88 | MAPT (0.60) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL29590480 | 0.88 | MAPT (0.60) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL14783169 | 0.88 | MAPT (0.49) | MAPTBRAF | |
| SCHEMBL14786483 | 0.88 | MAPT (0.44) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL29592435 | 0.88 | MAPT (0.49) | MAPTBRAF | |
| SCHEMBL28233924 | 0.88 | MAPT (0.49) | MAPTMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403531-A | Chemical entities, compositions, and methods as kinase inhibitors | 润新生物公司 | 2022-11-29 | — | — | CN | disclosed |
| CN-108794411-B | Certain chemical entities, compositions, and methods | 润新生物公司 | 2022-06-07 | — | — | CN | disclosed |