Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 7/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14783789 | 1.00 | HDAC3 (0.56) | HDAC3HDAC2TP53MAPTSMN1; SMN2 | |
| SCHEMBL15689137 | 0.93 | HDAC3 (0.56) | HDAC3HDAC2TP53MAPTSMN1; SMN2 | |
| SCHEMBL29590232 | 0.93 | MAPT (0.58) | HDAC3HDAC2TP53MAPTSMN1; SMN2 | |
| SCHEMBL14784329 | 0.93 | MAPT (0.58) | HDAC3HDAC2TP53MAPTSMN1; SMN2 | |
| SCHEMBL14784010 | 0.92 | HDAC3 (0.57) | HDAC3HDAC2MAPTHDAC1KCNQ3 | |
| SCHEMBL29590918 | 0.92 | HDAC3 (0.55) | HDAC3HDAC2MAPTSMN1; SMN2HDAC1 | |
| SCHEMBL29590180 | 0.92 | HDAC3 (0.57) | HDAC3HDAC2MAPTHDAC1KCNQ3 | |
| SCHEMBL14783300 | 0.92 | HDAC3 (0.55) | HDAC3HDAC2MAPTSMN1; SMN2HDAC1 | |
| SCHEMBL14784095 | 0.91 | HDAC3 (0.51) | HDAC3HDAC2TP53MAPTSMN1; SMN2 | |
| SCHEMBL29590369 | 0.91 | HDAC3 (0.51) | HDAC3HDAC2TP53MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403531-A | Chemical entities, compositions, and methods as kinase inhibitors | 润新生物公司 | 2022-11-29 | — | — | CN | disclosed |
| CN-108794411-B | Certain chemical entities, compositions, and methods | 润新生物公司 | 2022-06-07 | — | — | CN | disclosed |