Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 5/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.55 |
| ▸ | KCNQ3 | O43525 | 7/20 | 0.51 |
| ▸ | KCNQ2 | O43526 | 7/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.41 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14783300 | 1.00 | HDAC3 (0.55) | HDAC3HDAC2KCNQ3KCNQ2HDAC1 | |
| SCHEMBL29590180 | 0.93 | HDAC3 (0.57) | HDAC3HDAC2KCNQ3KCNQ2HDAC1 | |
| SCHEMBL14784010 | 0.93 | HDAC3 (0.57) | HDAC3HDAC2KCNQ3KCNQ2HDAC1 | |
| SCHEMBL29592532 | 0.92 | HDAC3 (0.49) | HDAC3HDAC2KCNQ3KCNQ2HDAC1 | |
| SCHEMBL14783380 | 0.92 | HDAC3 (0.49) | HDAC3HDAC2KCNQ3KCNQ2HDAC1 | |
| SCHEMBL29590684 | 0.92 | KCNQ3 (0.61) | HDAC3HDAC2KCNQ3KCNQ2MAOB | |
| SCHEMBL14784267 | 0.92 | KCNQ3 (0.61) | HDAC3HDAC2KCNQ3KCNQ2MAOB | |
| SCHEMBL14783789 | 0.92 | HDAC3 (0.56) | HDAC3HDAC2KCNQ3KCNQ2HDAC1 | |
| SCHEMBL29590491 | 0.92 | HDAC3 (0.56) | HDAC3HDAC2KCNQ3KCNQ2HDAC1 | |
| SCHEMBL14783103 | 0.90 | KCNQ3 (0.63) | HDAC3HDAC2KCNQ3KCNQ2CDK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403531-A | Chemical entities, compositions, and methods as kinase inhibitors | 润新生物公司 | 2022-11-29 | — | — | CN | disclosed |
| CN-108794411-B | Certain chemical entities, compositions, and methods | 润新生物公司 | 2022-06-07 | — | — | CN | disclosed |