Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 10/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.45 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14784098 | 1.00 | MTOR (0.52) | MTORPIK3CAPIK3CGEPHX2TP53 | |
| SCHEMBL14783328 | 0.94 | PIK3CA (0.50) | MTORPIK3CAPIK3CGTP53ALDH1A1 | |
| SCHEMBL29591266 | 0.94 | PIK3CA (0.50) | MTORPIK3CAPIK3CGTP53ALDH1A1 | |
| SCHEMBL15688557 | 0.94 | MTOR (0.56) | MTORPIK3CAPIK3CGEPHX2TP53 | |
| SCHEMBL15689091 | 0.93 | MTOR (0.49) | MTORPIK3CAPIK3CGALDH1A1CNR1 | |
| SCHEMBL14786126 | 0.92 | RAB9A (0.52) | MTORPIK3CAPIK3CGTP53HTT | |
| SCHEMBL29591611 | 0.92 | RAB9A (0.52) | MTORPIK3CAPIK3CGTP53HTT | |
| SCHEMBL14783621 | 0.92 | CNR1 (0.56) | TP53ALDH1A1HPGDHTTCNR1 | |
| SCHEMBL29591331 | 0.92 | CNR1 (0.56) | TP53ALDH1A1HPGDHTTCNR1 | |
| SCHEMBL14784128 | 0.91 | MTOR (0.52) | MTORPIK3CAPIK3CGEPHX2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403531-A | Chemical entities, compositions, and methods as kinase inhibitors | 润新生物公司 | 2022-11-29 | — | — | CN | disclosed |
| CN-108794411-B | Certain chemical entities, compositions, and methods | 润新生物公司 | 2022-06-07 | — | — | CN | disclosed |