Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 10/20 | 0.46 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.43 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14783531 | 1.00 | MTOR (0.46) | MTORKCNQ3KCNQ2EPHX2LMNA | |
| SCHEMBL29590156 | 0.95 | LMNA (0.50) | MTORKCNQ3KCNQ2EPHX2LMNA | |
| SCHEMBL14783277 | 0.95 | LMNA (0.50) | MTORKCNQ3KCNQ2EPHX2LMNA | |
| SCHEMBL14783539 | 0.94 | PIK3CA (0.47) | MTORKCNQ3KCNQ2EPHX2LMNA | |
| SCHEMBL29590395 | 0.94 | PIK3CA (0.47) | MTORKCNQ3KCNQ2EPHX2LMNA | |
| SCHEMBL14783581 | 0.93 | MTOR (0.51) | MTORKCNQ3KCNQ2EPHX2LMNA | |
| SCHEMBL29591439 | 0.93 | MTOR (0.51) | MTORKCNQ3KCNQ2EPHX2LMNA | |
| SCHEMBL29591549 | 0.93 | MTOR (0.52) | MTORKCNQ3KCNQ2EPHX2PIK3CA | |
| SCHEMBL14783011 | 0.93 | MTOR (0.52) | MTORKCNQ3KCNQ2EPHX2PIK3CA | |
| SCHEMBL29591294 | 0.93 | KCNQ3 (0.54) | KCNQ3KCNQ2LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403531-A | Chemical entities, compositions, and methods as kinase inhibitors | 润新生物公司 | 2022-11-29 | — | — | CN | disclosed |
| CN-108794411-B | Certain chemical entities, compositions, and methods | 润新生物公司 | 2022-06-07 | — | — | CN | disclosed |