Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 5/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.49 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14783380 | 1.00 | HDAC3 (0.49) | HDAC3HDAC2CDK6HDAC1KCNQ3 | |
| SCHEMBL14783187 | 0.94 | HDAC3 (0.49) | HDAC3HDAC2CDK6HDAC1KCNQ3 | |
| SCHEMBL29590968 | 0.94 | HDAC3 (0.49) | HDAC3HDAC2CDK6HDAC1KCNQ3 | |
| SCHEMBL29591540 | 0.94 | HDAC3 (0.53) | HDAC3HDAC2CDK6HDAC1MTOR | |
| SCHEMBL14783333 | 0.94 | HDAC3 (0.53) | HDAC3HDAC2CDK6HDAC1MTOR | |
| SCHEMBL29590770 | 0.93 | HDAC3 (0.50) | HDAC3HDAC2CDK6HDAC1MTOR | |
| SCHEMBL14783281 | 0.93 | HDAC3 (0.50) | HDAC3HDAC2CDK6HDAC1MTOR | |
| SCHEMBL14783300 | 0.92 | HDAC3 (0.55) | HDAC3HDAC2CDK6HDAC1KCNQ3 | |
| SCHEMBL29590918 | 0.92 | HDAC3 (0.55) | HDAC3HDAC2CDK6HDAC1KCNQ3 | |
| SCHEMBL29590104 | 0.92 | KCNQ3 (0.49) | HDAC3HDAC2KCNQ3KCNQ2MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403531-A | Chemical entities, compositions, and methods as kinase inhibitors | 润新生物公司 | 2022-11-29 | — | — | CN | disclosed |
| CN-108794411-B | Certain chemical entities, compositions, and methods | 润新生物公司 | 2022-06-07 | — | — | CN | disclosed |