Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 9/20 | 0.49 |
| ▸ | F11 | P03951 | 3/20 | 0.48 |
| ▸ | TPSB2 | P20231 | 3/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | F7 | P08709 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23218660 | 1.00 | CFD (0.49) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL23218539 | 0.93 | CFD (0.49) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL29592710 | 0.93 | CFD (0.49) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL29852567 | 0.88 | CFD (0.42) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL23218386 | 0.88 | CFD (0.42) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL23218864 | 0.86 | CFD (0.43) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL29592081 | 0.86 | CFD (0.43) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL23218471 | 0.85 | CFD (0.70) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL29593162 | 0.85 | CFD (0.70) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL23218116 | 0.82 | CFD (0.48) | CFDF11TPSB2KLKB1PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041238-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |
| CN-114502168-A | Oral complement factor D inhibitors | 拜奥克里斯特制药公司 | 2022-05-13 | — | — | CN | disclosed |