SCHEMBL2959294

SCHEMBL2959294

COc1cc(O)c(C(=O)c2ccccc2)c(Cc2cc(OC)cc(O)c2C(=O)c2ccccc2)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.66
LMNA P02545 5/20 0.66
CYP2C19 P33261 4/20 0.66
ALDH1A1 P00352 3/20 0.66
HTT P42858 3/20 0.66
CYP1A2 P05177 2/20 0.66
PGR P06401 2/20 0.66
SLC6A2 P23975 2/20 0.66
CYP2D6 P10635 2/20 0.66
PDE4A P27815 1/20 0.66
MAPK1 P28482 1/20 0.66
HRH1 P35367 1/20 0.66
SLC6A3 Q01959 1/20 0.66
PDE4D Q08499 1/20 0.66
MAPT P10636 5/20 0.52
KDM4E B2RXH2 3/20 0.52
RECQL P46063 2/20 0.52
ABL1 P00519 1/20 0.52
POLB P06746 1/20 0.52
RIN1 Q13671 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28748279 0.90 HPGD (0.60) HPGDLMNACYP2C19ALDH1A1HTT
SCHEMBL11987164 0.89 MAPT (0.60) HPGDLMNACYP2C19ALDH1A1HTT
SCHEMBL1456378 0.87 HPGD (0.68) HPGDLMNACYP2C19ALDH1A1HTT
SCHEMBL12984020 0.83 PTGES (0.63) HPGDLMNACYP2C19ALDH1A1HTT
SCHEMBL28689599 0.81 CYP3A4 (0.61) HPGDLMNACYP2C19ALDH1A1HTT
SCHEMBL30384772 0.81 CYP3A4 (0.63) HPGDLMNACYP2C19ALDH1A1HTT
SCHEMBL9339191 0.81 CYP3A4 (0.63) HPGDLMNACYP2C19ALDH1A1HTT
SCHEMBL8648084 0.80 HPGD (0.59) HPGDLMNACYP2C19ALDH1A1HTT
Oxybenzone SCHEMBL6674080 0.80 HPGD (1.00) HPGDLMNACYP2C19ALDH1A1HTT
Oxybenzone SCHEMBL15551 0.80 HPGD (1.00) HPGDLMNACYP2C19ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1680465-A1 UV STABILIZING ADDITIVE COMPOSITION CYTEC TECHNOLOGY CORP. (US) 2006-07-19 EP claimed
WO-2005047384-A1 UV STABILIZING ADDITIVE COMPOSITION CYTEC TECHNOLOGY CORP. (US) 2005-05-26 WO claimed
US-7763184-B2 Light stabilizing liquid matter containing 2- (2-hydroxy-3-α-cumyl-5-tert-octylphenyl) -2h-benzotriazole DOUBLE BOND CHEM. IND. CO., LTD. (TW) 2010-07-27 US disclosed
US-20080156227-A1 Light stabilizing liquid matter containing 2- (2-hydroxy-3-alpha-cumyl-5-tert-octylphenyl) -2h-benzotriazole DOUBLE BOND CHEM. IND. CO., LTD. 2008-07-03 US disclosed
EP-1680465-A1 UV STABILIZING ADDITIVE COMPOSITION CYTEC TECHNOLOGY CORP. (US) 2006-07-19 EP disclosed
WO-2005047384-A1 UV STABILIZING ADDITIVE COMPOSITION CYTEC TECHNOLOGY CORP. (US) 2005-05-26 WO disclosed