Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 3/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | LPL | P06858 | 9/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 9/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20356417 | 1.00 | CSF1R (0.37) | CSF1RBACE1IRAK4LPLLIPG | |
| SCHEMBL30639701 | 0.88 | LPL (0.37) | CSF1RBACE1IRAK4LPLLIPG | |
| SCHEMBL26614656 | 0.88 | LPL (0.37) | CSF1RBACE1IRAK4LPLLIPG | |
| SCHEMBL19411754 | 0.85 | PIK3CD (0.41) | CSF1RBACE1IRAK4LPLLIPG | |
| SCHEMBL30538044 | 0.84 | CTSC (0.30) | — | |
| SCHEMBL29038850 | 0.84 | CTSC (0.30) | — | |
| SCHEMBL16932271 | 0.83 | CTSC (0.31) | — | |
| SCHEMBL782545 | 0.82 | DDB1 (0.42) | CSF1RIRAK4LPLLIPGPRMT5 | |
| SCHEMBL16475230 | 0.78 | LPL (0.40) | CSF1RLPLLIPGIDO1 | |
| SCHEMBL29455590 | 0.78 | CSF1R (0.37) | CSF1RIRAK4LPLLIPGPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108264512-B | Nitrogen-containing fused heterocyclic compound, preparation method, intermediate, composition and application thereof | 上海医药集团股份有限公司 | 2022-05-03 | — | — | CN | disclosed |