Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4846588 | 1.00 | CYP1A2 (0.63) | CYP1A2NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL28582795 | 0.85 | CYP1A2 (0.67) | CYP1A2NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL31325779 | 0.84 | CYP1A2 (0.66) | CYP1A2NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL713218 | 0.84 | CYP1A2 (0.66) | CYP1A2NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL8775312 | 0.84 | RAB9A (0.51) | CYP1A2NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL28002483 | 0.84 | CYP1A2 (0.53) | CYP1A2NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL24184680 | 0.83 | CYP1A2 (0.65) | CYP1A2NPC1RAB9ASMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL5787439 | 0.82 | CYP1A2 (0.64) | CYP1A2NPC1RAB9ASMN1; SMN2LMNA | |
| Ammonia Solution, Strong SCHEMBL29085625 | 0.82 | CYP1A2 (0.64) | CYP1A2NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL12386966 | 0.81 | CYP1A2 (0.68) | CYP1A2NPC1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119306674-A | Preparation method of 2-phenylquinazoline-4 (3H) ketone compound | 重庆医科大学 | 2025-01-14 | — | — | CN | claimed |
| CN-119874702-A | Isoquinoline quinazoline Process for preparing ketone compounds | 河南农业大学 | 2025-04-25 | — | — | CN | disclosed |
| CN-119528823-A | Synthesis method of 2-aryl quinazoline compound | 武汉科技大学 | 2025-02-28 | — | — | CN | disclosed |
| CN-119306674-A | Preparation method of 2-phenylquinazoline-4 (3H) ketone compound | 重庆医科大学 | 2025-01-14 | — | — | CN | disclosed |
| CN-115785002-B | Synthesis method of quinazoline heterocyclic derivative | 枣庄学院 | 2024-10-11 | — | — | CN | disclosed |
| CN-118530186-A | Synthesis method of quinazoline derivative | 多氟多新材料股份有限公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-118125985-A | Method for preparing quinazolinone by activating alkylbenzene benzyl site C (sp 3) -H bond by photo-generated chlorine free radical | 桂林理工大学 | 2024-06-04 | — | — | CN | disclosed |
| CN-117586179-A | GPR183 antagonist and synthetic method and application thereof | 中国人民解放军海军特色医学中心 | 2024-02-23 | — | — | CN | disclosed |
| CN-117229222-A | Method for synthesizing quinazoline by dehydrogenation of tetrahydroquinazoline | 西安石油大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-116377458-A | Method for electrochemically synthesizing quinazoline derivative | 安徽科技学院 | 2023-07-04 | — | — | CN | disclosed |
| CN-115785002-A | Synthetic method of quinazoline heterocyclic derivative | 枣庄学院 | 2023-03-14 | — | — | CN | disclosed |
| CN-114591251-A | Chiral aminoquinazoline compound and preparation method and application thereof | 华南理工大学 | 2022-06-07 | — | — | CN | disclosed |
| CN-113429390-B | Quinazoline derivatives and uses thereof | 苏州恩华生物医药科技有限公司 | 2022-04-15 | — | — | CN | disclosed |