Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 18/20 | 0.68 |
| ▸ | TPSB2 | P20231 | 6/20 | 0.68 |
| ▸ | F11 | P03951 | 6/20 | 0.68 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.68 |
| ▸ | PLAU | P00749 | 2/20 | 0.68 |
| ▸ | PLG | P00747 | 1/20 | 0.68 |
| ▸ | F7 | P08709 | 1/20 | 0.68 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.52 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.52 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23219221 | 1.00 | CFD (0.68) | CFDTPSB2F11KLKB1PLAU | |
| SCHEMBL23218421 | 0.90 | CFD (0.66) | CFDTPSB2F11KLKB1PLAU | |
| SCHEMBL29591063 | 0.90 | CFD (0.66) | CFDTPSB2F11KLKB1PLAU | |
| SCHEMBL29853034 | 0.88 | CFD (0.55) | CFDTPSB2F11KLKB1PLAU | |
| SCHEMBL23219107 | 0.88 | CFD (0.55) | CFDTPSB2F11KLKB1PLAU | |
| SCHEMBL23219166 | 0.87 | CFD (0.61) | CFDTPSB2F11KLKB1PLAU | |
| SCHEMBL29592789 | 0.87 | CFD (0.61) | CFDTPSB2F11KLKB1PLAU | |
| SCHEMBL23218224 | 0.87 | CFD (0.66) | CFDTPSB2F11KLKB1PLAU | |
| SCHEMBL29852585 | 0.87 | CFD (0.66) | CFDTPSB2F11KLKB1PLAU | |
| SCHEMBL23218231 | 0.85 | CFD (0.70) | CFDTPSB2F11KLKB1PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041238-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |
| CN-114502168-A | Oral complement factor D inhibitors | 拜奥克里斯特制药公司 | 2022-05-13 | — | — | CN | disclosed |