Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | TEC | P42680 | 1/20 | 0.41 |
| ▸ | TXK | P42681 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21783734 | 0.95 | TEC (0.47) | PTGDR2TECTXKTMEM97SIGMAR1 | |
| SCHEMBL14651433 | 0.95 | TEC (0.47) | PTGDR2TECTXKTMEM97SIGMAR1 | |
| SCHEMBL20411768 | 0.94 | TEC (0.45) | PTGDR2TECTXKTMEM97SIGMAR1 | |
| SCHEMBL28348501 | 0.86 | PREP (0.41) | PTGDR2TECTXK | |
| SCHEMBL28348505 | 0.86 | PREP (0.41) | PTGDR2TECTXK | |
| SCHEMBL30565889 | 0.85 | BTK (0.42) | PTGDR2POLB | |
| SCHEMBL15878607 | 0.84 | PREP (0.39) | PTGDR2TMEM97SIGMAR1 | |
| SCHEMBL14637258 | 0.84 | TEC (0.56) | TECTXK | |
| SCHEMBL14651434 | 0.84 | TEC (0.56) | TECTXK | |
| SCHEMBL21056239 | 0.84 | JAK2 (0.46) | GRIN2BNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715626-B | Heterocyclic compounds as FGFR inhibitors | 广州诺诚健华医药科技有限公司 | 2022-04-26 | — | — | CN | disclosed |