Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 8/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10957005 | 0.89 | CYP2A6 (0.55) | CYP2A6PTGS2CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL11067761 | 0.84 | PTGS2 (0.60) | CYP2A6PTGS2CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL30032 | 0.83 | PTGS2 (0.64) | CYP2A6PTGS2CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL28181896 | 0.83 | PTGS2 (0.64) | CYP2A6PTGS2CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL31635952 | 0.83 | PTGS2 (0.64) | CYP2A6PTGS2CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL28577920 | 0.82 | PTGS2 (0.59) | CYP2A6PTGS2CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL16026628 | 0.82 | PTGS2 (0.62) | CYP2A6PTGS2CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL16026793 | 0.82 | PTGS2 (0.62) | CYP2A6PTGS2CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL1323698 | 0.82 | PTGS2 (0.62) | CYP2A6PTGS2CYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL16026561 | 0.82 | PTGS2 (0.62) | CYP2A6PTGS2CYP3A4ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104926819-A | Synthesis method of 2,8-diaryl(amino) Troger's base derivatives | UNIV JIANGSU NORMAL | 2015-09-23 | — | — | CN | claimed |
| CN-105601558-B | A kind of electron-transporting type luminescent material and its application | 中节能万润股份有限公司 | 2018-09-18 | — | — | CN | disclosed |
| CN-104926819-B | Synthetic method and its anti-human liver cancer the HepG2 activity of 2,8 diaryl (amino) Chao Geer alkali derivants | 江苏师范大学 | 2017-11-03 | — | — | CN | disclosed |
| CN-105601558-A | Electronic-transmission luminescent material and application thereof | CECEP VALIANT CO LTD | 2016-05-25 | — | — | CN | disclosed |
| CN-104926819-A | Synthesis method of 2,8-diaryl(amino) Troger's base derivatives | UNIV JIANGSU NORMAL | 2015-09-23 | — | — | CN | disclosed |
| US-7772431-B1 | Performance of energy storage devices: potential areas for dendritic chemistry involvement | NEWKOME GEORGE R | 2010-08-10 | — | — | US | disclosed |
| US-7250534-B1 | Performance of energy storage devices: potential areas for dendritic chemistry involvement | UNIVERSITY OF SOUTH FLORIDA (US) | 2007-07-31 | — | — | US | disclosed |
| WO-2001007497-A2 | PERFORMANCE OF ENERGY STORAGE DEVICES: POTENTIAL AREAS FOR DENDRITIC CHEMISTRY INVOLVEMENT | UNIVERSITY OF SOUTH FLORIDA (US) | 2001-02-01 | — | — | WO | disclosed |
| CN-1162317-A | Functional terpyridine metal complexes, methods for their preparation and oligonucleotide conjugates with terpyridine metal complexes | NOVATIS CO (CH) | 1997-10-15 | — | — | CN | disclosed |
| CN-1162316-A | Oligonucleotide conjugates, compositions and methods for splitting ribonucleic acids | NOVATIS CO (CH) | 1997-10-15 | — | — | CN | disclosed |