Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | HCRTR2 | O43614 | 11/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 9/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CFTR | P13569 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12150154 | 0.80 | HCRTR2 (0.45) | HCRTR2HCRTR1 | |
| SCHEMBL27787386 | 0.79 | MYC (0.54) | MYCKDM4EPOLBATMHCRTR2 | |
| SCHEMBL16040983 | 0.79 | CYP46A1 (0.49) | MYCHCRTR2HCRTR1 | |
| SCHEMBL28536420 | 0.79 | MYC (0.50) | MYCKDM4EPOLBATMTSHR | |
| SCHEMBL15434915 | 0.78 | MYC (0.66) | MYCKDM4EPOLBATMTSHR | |
| SCHEMBL30006500 | 0.78 | ALDH1A1 (0.56) | MYCKDM4EPOLBHCRTR2HCRTR1 | |
| SCHEMBL1586233 | 0.78 | ALDH1A1 (0.56) | MYCKDM4EPOLBHCRTR2HCRTR1 | |
| SCHEMBL19893901 | 0.78 | HSD17B10 (0.47) | MYCHCRTR2HCRTR1TSHRALDH1A1 | |
| SCHEMBL17559746 | 0.78 | GAA (0.51) | KDM4EATMHCRTR2HCRTR1TSHR | |
| SCHEMBL31621959 | 0.77 | CA12 (0.65) | KDM4EHCRTR2HCRTR1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555603-A | Improved synthesis for the preparation of (2H-1,2, 3-triazol-2-yl) phenyl compounds as orexin receptor modulators | 詹森药业有限公司 | 2022-05-27 | — | — | CN | disclosed |