Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.67 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.53 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.42 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28901274 | 1.00 | TAAR1 (0.67) | TAAR1OPRL1OGFRL1MAPK1HTT | |
| SCHEMBL28901279 | 1.00 | TAAR1 (0.67) | TAAR1OPRL1OGFRL1MAPK1HTT | |
| SCHEMBL16698862 | 0.84 | SCN9A (0.68) | TAAR1OPRL1OGFRL1SCN9ACHRM1 | |
| SCHEMBL16698864 | 0.84 | SCN9A (0.68) | TAAR1OPRL1OGFRL1SCN9ACHRM1 | |
| SCHEMBL13506137 | 0.82 | TAAR1 (0.51) | TAAR1OPRL1OGFRL1ACHE | |
| SCHEMBL13506138 | 0.82 | TAAR1 (0.51) | TAAR1OPRL1OGFRL1ACHE | |
| SCHEMBL29596539 | 0.80 | TAAR1 (1.00) | TAAR1OPRL1OGFRL1CHRM1HRH1 | |
| SCHEMBL28901283 | 0.80 | TAAR1 (1.00) | TAAR1OPRL1OGFRL1CHRM1HRH1 | |
| SCHEMBL28901262 | 0.80 | TAAR1 (1.00) | TAAR1OPRL1OGFRL1CHRM1HRH1 | |
| SCHEMBL29597012 | 0.80 | TAAR1 (1.00) | TAAR1OPRL1OGFRL1CHRM1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114349781-B | Chiral tetrahydropyrrole skeleton-containing aminophenoxy zinc complex and preparation method and application thereof | 华东理工大学 | 2024-09-24 | — | — | CN | disclosed |
| CN-114349781-A | Chiral pyrrolidine skeleton-containing aminophenoxy zinc complex and preparation method and application thereof | 华东理工大学 | 2022-04-15 | — | — | CN | disclosed |