SCHEMBL29598604

SCHEMBL29598604

COC(C=O)C(C)(C)C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 1/20 0.32
SLC1A2 P43004 1/20 0.32
SLC1A1 P43005 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25213020 0.80 ALDH1A1 (0.31) ALDH1A1TSHR
SCHEMBL4041071 0.72
SCHEMBL2419413 0.69 SLC1A3 (0.31) SLC1A3SLC1A2SLC1A1
SCHEMBL7783013 0.69 ALDH1A1 (0.36) SLC1A3SLC1A2SLC1A1ALDH1A1TSHR
SCHEMBL3913617 0.69 ALDH1A1 (0.36) ALDH1A1TSHR
SCHEMBL7148528 0.68 SLC1A3 (0.33) SLC1A3SLC1A2SLC1A1
SCHEMBL8117959 0.67 ALDH1A1 (0.36) SLC1A3SLC1A2SLC1A1ALDH1A1TSHR
SCHEMBL2637176 0.67 ALDH1A1 (0.35) ALDH1A1TSHR
SCHEMBL17866814 0.65
SCHEMBL7152305 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114450283-B 3, 6-Diamino-pyridazin-3-yl derivatives, pharmaceutical compositions containing them and their use as pro-apoptotic agents 法国施维雅药厂 2024-05-07 CN disclosed
CN-114450283-A 3, 6-diamino-pyridazin-3-yl derivatives, pharmaceutical compositions containing them and their use as pro-apoptotic agents 法国施维雅药厂 2022-05-06 CN disclosed