SCHEMBL29599396

SCHEMBL29599396

CC(C)[C@H](NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ OPRD1 P41143 14/20 0.62
▸ OPRM1 P35372 9/20 0.62
▸ OPRK1 P41145 2/20 0.62
▸ MME P08473 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31134340 0.87 OPRD1 (0.72) OPRD1OPRM1OPRK1
SCHEMBL30445403 0.86 OPRD1 (0.50) OPRD1OPRM1OPRK1
SCHEMBL29350612 0.85 ACE (0.58) OPRD1OPRM1OPRK1MME
SCHEMBL30017516 0.85 MME (0.70) OPRD1OPRM1OPRK1MME
SCHEMBL30017589 0.85 MME (0.70) OPRD1OPRM1OPRK1MME
SCHEMBL8432968 0.85 OPRD1 (0.59) OPRD1OPRM1OPRK1
SCHEMBL8432975 0.85 OPRD1 (0.59) OPRD1OPRM1OPRK1
SCHEMBL29519497 0.84 OPRD1 (0.62) OPRD1OPRM1OPRK1MME
SCHEMBL29519462 0.84 OPRD1 (0.62) OPRD1OPRM1OPRK1MME
SCHEMBL29519472 0.84 OPRD1 (0.62) OPRD1OPRM1OPRK1MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250034215-A1 MULTI-DISULFIDE-BOND LONG-CHAIN PEPTIDE WITH NEUROPROTECTIVE ACTIVITY, PHARMACEUTICAL COMPOSITION AND APPLICATION NANTONG UNIVERSITY (CN) 2025-01-30 — — US claimed
US-20230151065-A1 MULTI-DISULFIDE-BOND LONG-CHAIN PEPTIDE WITH NEUROPROTECTIVE ACTIVITY, PHARMACEUTICAL COMPOSITION AND APPLICATION NANTONG UNIVERSITY (CN) 2023-05-18 — — US claimed
US-20250034215-A1 MULTI-DISULFIDE-BOND LONG-CHAIN PEPTIDE WITH NEUROPROTECTIVE ACTIVITY, PHARMACEUTICAL COMPOSITION AND APPLICATION NANTONG UNIVERSITY (CN) 2025-01-30 — — US disclosed
US-20230151065-A1 MULTI-DISULFIDE-BOND LONG-CHAIN PEPTIDE WITH NEUROPROTECTIVE ACTIVITY, PHARMACEUTICAL COMPOSITION AND APPLICATION NANTONG UNIVERSITY (CN) 2023-05-18 — — US disclosed
CN-111217894-B Multi-disulfide long-chain peptide with neuroprotective activity, pharmaceutical composition and application 中国科学院大连化学物理研究所 2022-05-31 — — CN disclosed
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