Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24362563 | 1.00 | P2RX7 (0.36) | P2RX7 | |
| SCHEMBL24362406 | 0.82 | P2RX7 (0.37) | P2RX7 | |
| SCHEMBL24362399 | 0.80 | P2RX7 (0.37) | P2RX7 | |
| SCHEMBL29599462 | 0.80 | P2RX7 (0.37) | P2RX7 | |
| SCHEMBL24362727 | 0.78 | P2RX7 (0.34) | P2RX7 | |
| SCHEMBL24362732 | 0.78 | USP2 (0.35) | — | |
| SCHEMBL29599373 | 0.73 | P2RX7 (0.37) | P2RX7 | |
| SCHEMBL26676496 | 0.73 | P2RX7 (0.37) | P2RX7 | |
| SCHEMBL24357327 | 0.73 | P2RX7 (0.39) | P2RX7 | |
| SCHEMBL29919188 | 0.72 | MAPT (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4228758-A1 | SUBSTITUTED 6,7-DIHYDRO-5H-BENZO[7]ANNULENE COMPOUNDS AND THEIR DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | Sanofi (FR) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022084280-A1 | SUBSTITUTED 6,7-DIHYDRO-5H-BENZO[7]ANNULENE COMPOUNDS AND THEIR DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2022-04-28 | — | — | WO | disclosed |