Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | SLC18A3 | Q16572 | 5/20 | 0.42 |
| ▸ | FABP7 | O15540 | 3/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22830852 | 1.00 | AKR1C3 (0.43) | AKR1C3AKR1C1SLC18A3FABP7FABP5 | |
| SCHEMBL22830919 | 1.00 | AKR1C3 (0.43) | AKR1C3AKR1C1SLC18A3FABP7FABP5 | |
| SCHEMBL22492144 | 1.00 | AKR1C3 (0.43) | AKR1C3AKR1C1SLC18A3FABP7FABP5 | |
| SCHEMBL8327892 | 0.89 | AKR1C3 (0.50) | AKR1C3AKR1C1FABP7FABP5LMNA | |
| SCHEMBL8327889 | 0.89 | AKR1C3 (0.50) | AKR1C3AKR1C1FABP7FABP5LMNA | |
| SCHEMBL28441912 | 0.79 | MAPT (0.51) | MAPTHTTCYP2D6CYP1A2TSHR | |
| SCHEMBL9169697 | 0.76 | SLC18A3 (0.41) | SLC18A3 | |
| SCHEMBL4522521 | 0.76 | KCNQ3 (0.53) | AKR1C3AKR1C1FABP7FABP5LMNA | |
| SCHEMBL7352068 | 0.76 | KCNQ3 (0.53) | AKR1C3AKR1C1FABP7FABP5LMNA | |
| SCHEMBL7352063 | 0.76 | KCNQ3 (0.53) | AKR1C3AKR1C1FABP7FABP5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11332472-B2 | Substituted piperidines as inhibitors of ubiquitin specific protease 7 | LES LABORATOIRES SERVIER (FR) | 2022-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11332472-B2 | Substituted piperidines as inhibitors of ubiquitin specific protease 7 | USP7, PSMA7, PSMB7 | AKR1C3 3208/4885AKR1C1 3656/4885SLC18A3 4477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.