SCHEMBL2959986

SCHEMBL2959986

CC1=CC(c2cccc3ccccc23)c2cccc(Br)c21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.37
ALDH1A1 P00352 2/20 0.36
CYP2A6 P11509 1/20 0.36
SLC6A4 P31645 6/20 0.35
SLC6A2 P23975 2/20 0.34
SLC6A3 Q01959 2/20 0.34
KDM4E B2RXH2 1/20 0.34
TDP2 O95551 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
ALOX12 P18054 1/20 0.34
MAPK1 P28482 1/20 0.34
CASP3 P42574 1/20 0.34
HTT P42858 1/20 0.34
GALK1 P51570 1/20 0.34
BLM P54132 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2960706 0.82 PBRM1 (0.46) KDM1AALDH1A1PBRM1
SCHEMBL2975049 0.79 KDM4E (0.38) KDM1AALDH1A1CYP2A6SLC6A4SLC6A2
SCHEMBL2973832 0.79 GID4 (0.37) KDM1AALDH1A1PBRM1
SCHEMBL2965300 0.78 KDM4E (0.36) CYP2A6SLC6A4SLC6A2SLC6A3KDM4E
SCHEMBL2959658 0.78 PBRM1 (0.38) ALDH1A1PBRM1
SCHEMBL2959907 0.76 CYP1A2 (0.39) KDM1AALDH1A1CYP2A6SLC6A4SLC6A2
SCHEMBL2956770 0.75 CYP1A2 (0.35) KDM1AALDH1A1CYP2A6SLC6A4SLC6A2
SCHEMBL2975128 0.72 PBRM1 (0.34) ALDH1A1PBRM1
SCHEMBL2970600 0.71 PBRM1 (0.36) ALDH1A1PBRM1
Hydrochloric Acid SCHEMBL5616456 0.68 PBRM1 (0.35) ALDH1A1PBRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7763562-B2 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-07-27 US disclosed
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-06-14 US disclosed
WO-2006065809-A2 HETEROATOM BRIDGED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135597-A1 Heteroatom bridged metallocene compounds for olefin polymerization AP2M1, AP1M1, PYM1 KDM1A 3280/4885ALDH1A1 4332/4885CYP2A6 2465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.