Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.74 |
| ▸ | CACNA1C | Q13936 | 5/20 | 0.74 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.74 |
| ▸ | MEN1 | O00255 | 4/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.74 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.74 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.74 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.74 |
| ▸ | CCKBR | P32239 | 2/20 | 0.74 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.74 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.74 |
| ▸ | MLNR | O43193 | 1/20 | 0.74 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.74 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9187081 | 1.00 | MAPT (1.00) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4797073 | 0.89 | CYP1A2 (0.92) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7446251 | 0.86 | MAPT (0.75) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10823937 | 0.86 | MAPT (0.75) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| Isradipine SCHEMBL3070351 | 0.86 | CYP1A2 (0.81) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| Isradipine SCHEMBL1172992 | 0.85 | CYP2C9 (1.00) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| (S)-Isradipine SCHEMBL34557 | 0.85 | CYP2C9 (1.00) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| (R)-Isradipine SCHEMBL34556 | 0.85 | CYP2C9 (1.00) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10924747 | 0.85 | CYP1A2 (0.84) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4797084 | 0.85 | CYP1A2 (0.84) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4578941-A2 | COMBINED CHEMICAL AND GENETIC APPROACHES FOR GENERATION OF INDUCED PLURIPOTENT STEM CELLS | The Scripps Research Institute (US) | 2025-07-02 | — | — | EP | disclosed |
| EP-4438734-A2 | REPROGRAMMING OF CELLS TO A NEW FATE | The Scripps Research Institute (US) | 2024-10-02 | — | — | EP | disclosed |
| EP-3399026-B1 | REPROGRAMMING OF CELLS TO A NEW FATE | SCRIPPS RESEARCH INST (US) | 2024-06-26 | — | — | EP | disclosed |
| US-11332716-B2 | Methods and compositions for producing pancreatic beta cells | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11332716-B2 | Methods and compositions for producing pancreatic beta cells | IAPP, ALPG, AMY2A | MAPT 4517/4885CYP1A2 4820/4885CYP3A4 4821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.