AMY2A

Pancreatic alpha-amylase · P04746 · AMY2A on Sugi Atlas →

5,969 patent compounds predicted against AMY2A, 3,770 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL7763081	0.49	10/20
Acarbose (SCHEMBL16848)	1.00	9/20
Acarbose (SCHEMBL16849)	1.00	9/20
Acarbose (SCHEMBL611277)	1.00	9/20
Acarbose (SCHEMBL681337)	1.00	9/20
Acarbose (SCHEMBL4068725)	1.00	9/20
Acarbose (SCHEMBL4121036)	1.00	9/20
Acarbose (SCHEMBL4121040)	1.00	9/20
SCHEMBL4313896	1.00	9/20
SCHEMBL4314669	1.00	9/20
SCHEMBL4321098	1.00	9/20
Acarbose (SCHEMBL5316305)	1.00	9/20
Acarbose (SCHEMBL690901)	0.93	9/20
Acarbose (SCHEMBL692582)	0.91	9/20
SCHEMBL5161028	0.88	9/20
SCHEMBL5161010	0.87	9/20
Acarbose (SCHEMBL2320932)	0.86	9/20
Acarbose (SCHEMBL7601414)	0.81	9/20
Acarbose (SCHEMBL536524)	0.80	9/20
Acarbose (SCHEMBL2345914)	0.78	9/20

Clinical trials — most relevant to AMY2A by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
A Confirmatory Clinical Study in NSCLC Patients With MET Exon 14 Mutation (KUNPENG-2)	PHASE3	RECRUITING
A Double-Blind, Placebo-Controlled Study of Fermented Deglycyrrhizinated Licorice Extract	PHASE2	COMPLETED
HP-211 Safety and Proof of Concept Dose Ranging Study in Patients With Type 2 Diabetes	PHASE2	RECRUITING
A Trial to Assess the Effect of Kidney Impairment on How AMG 133 is Absorbed, Broken Down, and Eliminated by the Body	PHASE1	COMPLETED
Acute Effect of HP-211 (Axulin) on Blood Glucose and Serum Insulin Responses in Healthy Lean and Overweight Humans	PHASE1	COMPLETED
Acute Pancreatitis Targets (APT) Study	nan	COMPLETED
Translation and Validation of Chinese COMPAT-SF	nan	RECRUITING
Dexmedetomidine and Propofol in Mechanically Ventilated Patients by Using Salivary Alpha-amylase as a Stress Marker	nan	COMPLETED
Utility of Trypsinogen -2 in Early Detection and Follow Up of Post-pancreatectomy Acute Pancreatitis (PPAP)	nan	RECRUITING
Perioperative Salivary Alpha-amylase as a Predictor of Delirium After Lower Extremity Vascular Bypass Surgery	nan	COMPLETED
Effects of Seaweed Extract on Postprandial Response to White Bread	nan	UNKNOWN
Markers in Acute Pancreatitis-1	nan	COMPLETED
Effect of Proprietary Botanical Blend on Glycemic Control and Post-prandial Carbohydrate Absorption	nan	UNKNOWN
Long-term Health After Severe Acute Malnutrition in Children and Adults: the Role of the Pancreas	nan	COMPLETED
Randomized Trial of Aggressive Fluid Hydration to Prevent Post ERCP Pancreatitis	nan	COMPLETED
The Evaluation of Pro/Antioxidative Profile and Diagnostic Parameters in the Patients With Pancreatic Disease	nan	COMPLETED
Entral Feeding in Acute Severe Pancreatitis	nan	COMPLETED
Clinical and Economic Validation of the ISGPS Definition of PPAP	nan	COMPLETED
Small Intestinal Bacterial Overgrowth (SIBO) in Pancreatic Adenocarcinoma (PDAC)	nan	RECRUITING
EUS-guided FNB-induced PANCREatitis Assessment	nan	RECRUITING
Early Oral Refeeding in Mild Acute Pancreatitis	nan	COMPLETED
Interest of the Sialendoscopy Associated With a Local Injection of Corticosteroids in the Treatment of Radio-induced Xerostomia in Comparison With the Hygiene Rules	nan	UNKNOWN
A Case-control Study Comparing Glycaemic Control in Pancreatic Cancer Patients vs Healthy Matched Individuals.	nan	COMPLETED
Allopurinol in Prevention of Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis	nan	COMPLETED
A Proof-of-Concept Study Evaluating LINFU™	nan	COMPLETED
Pancreatic Exocrine Insufficiency in Acute Pancreatitis	nan	COMPLETED
Select Indian Ragas on Electrophysiological Parameters	nan	COMPLETED
Tracheal Dosage of Amylase : a New Surrogate for Microaspirations in Ventilated ICU Patients	nan	COMPLETED
Predicting Pancreatic Necrosis Using mitDNA	nan	UNKNOWN
Intramuscular Diclofenac in the Prevention of Post-ERCP Pancreatitis	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a AMY2A binder may also engage these)

Protein	Name	Similarity
P19961	—	1.000	P19961 →
P0DTE7	—	1.000	P0DTE7 →
AMY1A	Alpha-amylase 1A	1.000	landscape →
P00689	—	1.000	P00689 →
P0DTE8	—	0.999	P0DTE8 →
P00688	—	0.997	P00688 →
P00690	—	0.996	P00690 →
P00687	—	0.995	P00687 →
P83053	—	0.993	P83053 →
H2N0D4	—	0.985	H2N0D4 →
P54215	—	0.971	P54215 →
Q23835	—	0.971	Q23835 →
P08144	—	0.970	P08144 →
O18345	—	0.970	O18345 →
Q9BN01	—	0.966	Q9BN01 →
P17859	—	0.964	P17859 →
P83833	—	0.964	P83833 →
P27937	—	0.963	P27937 →
P81641	—	0.963	P81641 →
P09107	—	0.961	P09107 →
P04063	—	0.960	P04063 →
P27939	—	0.960	P27939 →
P04747	—	0.956	P04747 →
P56634	—	0.955	P56634 →
P27934	—	0.954	P27934 →
P91778	—	0.953	P91778 →
O18552	—	0.953	O18552 →
O77011	—	0.952	O77011 →
O18420	—	0.951	O18420 →
O77016	—	0.950	O77016 →