Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30548823 | 1.00 | SLC6A3 (0.44) | SLC6A3ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL24357853 | 1.00 | SLC6A3 (0.44) | SLC6A3ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL31379004 | 0.94 | SLC6A3 (0.42) | SLC6A3ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL23551037 | 0.94 | SLC6A3 (0.42) | SLC6A3ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL23528113 | 0.94 | SLC6A3 (0.42) | SLC6A3ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL19230575 | 0.90 | SLC6A2 (0.41) | SLC6A3ALDH1A1SLC6A2SLC6A4ATM | |
| SCHEMBL24429131 | 0.84 | SLC6A2 (0.39) | SLC6A3ALDH1A1SLC6A2SLC6A4SRD5A1 | |
| SCHEMBL24357662 | 0.83 | SLC6A3 (0.42) | SLC6A3ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL29545631 | 0.83 | SLC6A3 (0.42) | SLC6A3ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL24357660 | 0.82 | SLC6A3 (0.42) | SLC6A3ALDH1A1KDM4EGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119451943-A | Novel substituted 4-amino-4-oxo-but-2-enyl derivatives, process for their preparation and their therapeutic use | 赛诺菲 | 2025-02-14 | — | — | CN | disclosed |
| CN-119032079-A | Novel substituted fluorinated vinyl-N-propyl-pyrrolidine compounds, process for their preparation and their therapeutic use | 赛诺菲 | 2024-11-26 | — | — | CN | disclosed |
| CN-119013254-A | Novel substituted fluorinated N-propyl-pyrrolidine and N-propyl-azetidine compounds, processes for their preparation and their therapeutic use | 赛诺菲 | 2024-11-22 | — | — | CN | disclosed |
| CN-118984820-A | Novel substituted fluorinated N-propyl-pyrrolidine compounds, methods for the preparation thereof and therapeutic uses thereof | 赛诺菲 | 2024-11-19 | — | — | CN | disclosed |
| EP-4228758-A1 | SUBSTITUTED 6,7-DIHYDRO-5H-BENZO[7]ANNULENE COMPOUNDS AND THEIR DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | Sanofi (FR) | 2023-08-23 | — | — | EP | disclosed |
| CN-116615413-A | Substituted 6, 7-dihydro-5H-benzo [7] rotaline compounds and derivatives thereof, method for the production and therapeutic use thereof | 赛诺菲 | 2023-08-18 | — | — | CN | disclosed |
| WO-2022084280-A1 | SUBSTITUTED 6,7-DIHYDRO-5H-BENZO[7]ANNULENE COMPOUNDS AND THEIR DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2022-04-28 | — | — | WO | disclosed |