Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31254127 | 1.00 | ALDH1A1 (0.44) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL12406 | 1.00 | ALDH1A1 (0.44) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL29047204 | 0.82 | ALDH1A1 (0.33) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| Benzofuran SCHEMBL29153281 | 0.81 | KDM4E (0.36) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL28304525 | 0.79 | CCR1 (0.55) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL8193 | 0.79 | CCR1 (0.55) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL29354893 | 0.79 | CCR1 (0.55) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL30323275 | 0.79 | — | — | |
| Ammonia Solution, Strong SCHEMBL2732606 | 0.76 | CCR1 (0.52) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL16337846 | 0.76 | CCR1 (0.52) | ALDH1A1KDM4ELMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957218-A | Piperidine amine compound containing fused ring pyrimidine and preparation method and application thereof | 沈阳中化农药化工研发有限公司 | 2022-08-30 | — | — | CN | claimed |
| US-20250250282-A1 | NOVEL SEVEN-MEMBERED RING-FUSED COMPOUNDS | Prism BioLab Co., Ltd. (JP) | 2025-08-07 | — | — | US | disclosed |
| EP-4508052-A1 | NOVEL SEVEN-MEMBERED RING-FUSED COMPOUNDS | PRISM BioLab Co., Ltd. (JP) | 2025-02-19 | — | — | EP | disclosed |
| CN-119013278-A | Novel seven-membered ring fused compounds | 株式会社棱镜生物实验室 | 2024-11-22 | — | — | CN | disclosed |
| US-20240309006-A1 | NOVEL BICYCLIC COMPOUNDS | Prism BioLab Co., Ltd. (JP) | 2024-09-19 | — | — | US | disclosed |
| CN-110740996-B | Covalent small molecule DCN1 inhibitors and methods of treatment using the same | 密执安大学评议会 | 2024-01-09 | — | — | CN | disclosed |
| EP-4281456-A1 | NOVEL BICYCLIC COMPOUNDS | PRISM BioLab Co., Ltd. (JP) | 2023-11-29 | — | — | EP | disclosed |
| US-20230374034-A1 | NOVEL BICYCLIC COMPOUNDS | Prism BioLab Co., Ltd. (JP) | 2023-11-23 | — | — | US | disclosed |
| WO-2023200017-A1 | NOVEL SEVEN-MEMBERED RING-FUSED COMPOUNDS | Prism BioLab Co., Ltd. (JP) | 2023-10-19 | — | — | WO | disclosed |
| EP-4225760-A1 | NOVEL BICYCLIC COMPOUNDS | PRISM BioLab Co., Ltd. (JP) | 2023-08-16 | — | — | EP | disclosed |
| WO-2023140369-A1 | PHOSPHORIC ACID DERIVATIVES | Prism BioLab Co., Ltd. (JP) | 2023-07-27 | — | — | WO | disclosed |
| CN-116348119-A | Novel bicyclic compounds | 株式会社棱镜生物实验室 | 2023-06-27 | — | — | CN | disclosed |
| EP-4182317-A1 | NOVEL HETEROCYCLIC COMPOUNDS | PRISM BioLab Co., Ltd. (JP) | 2023-05-24 | — | — | EP | disclosed |
| CN-116018345-A | Novel heterocyclic compounds | 株式会社棱镜生物实验室 | 2023-04-25 | — | — | CN | disclosed |
| WO-2022158610-A1 | NOVEL BICYCLIC COMPOUNDS | Prism BioLab Co., Ltd. (JP) | 2022-07-28 | — | — | WO | disclosed |
| WO-2022075486-A1 | NOVEL BICYCLIC COMPOUNDS | Prism BioLab Co., Ltd. (JP) | 2022-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230374034-A1 | NOVEL BICYCLIC COMPOUNDS | NOTCH1, NOTCH2, HES1 | ALDH1A1 1622/4885KDM4E 1654/4885LMNA 2319/4885 |
| US-20240309006-A1 | NOVEL BICYCLIC COMPOUNDS | NOTCH1, NOTCH2, HES1 | ALDH1A1 1423/4885KDM4E 1617/4885LMNA 2371/4885 |
| US-20250250282-A1 | NOVEL SEVEN-MEMBERED RING-FUSED COMPOUNDS | NOTCH1, NOTCH2, NOTCH4 | ALDH1A1 2685/4885KDM4E 2182/4885LMNA 3551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.