Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.67 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 16/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 16/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 13/20 | 0.46 |
| ▸ | LPL | P06858 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24359561 | 1.00 | KCNH2 (0.67) | KCNH2LTA4HHDAC1HDAC2HDAC3 | |
| SCHEMBL29600299 | 0.82 | PDE7A (0.47) | KCNH2LTA4HHDAC1HDAC2HDAC3 | |
| SCHEMBL29598145 | 0.81 | KCNH2 (1.00) | KCNH2LTA4HHDAC1HDAC2HDAC3 | |
| SCHEMBL2873589 | 0.81 | KCNH2 (1.00) | KCNH2LTA4HHDAC1HDAC2HDAC3 | |
| SCHEMBL28154361 | 0.79 | LTA4H (0.50) | KCNH2LTA4HHDAC1HDAC2HDAC3 | |
| SCHEMBL29217101 | 0.78 | KCNH2 (0.44) | KCNH2LTA4HHDAC1HDAC2HDAC3 | |
| SCHEMBL26115422 | 0.78 | KCNH2 (0.46) | KCNH2 | |
| SCHEMBL26111393 | 0.76 | HDAC1 (0.41) | KCNH2HDAC1HDAC2HDAC3 | |
| SCHEMBL11729689 | 0.76 | KCNH2 (0.46) | KCNH2HDAC1HDAC2HDAC3 | |
| SCHEMBL613358 | 0.74 | CYP3A4 (0.48) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116348114-A | Thiobenzimidazole derivatives or pharmaceutically acceptable salts thereof and use thereof | 高丽大学校产学协力团 | 2023-06-27 | — | — | CN | disclosed |
| WO-2022086110-A1 | THIOBENZIMIDAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND USE THEREOF | 고려대학교 산학협력단 | 2022-04-28 | — | — | WO | disclosed |