Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 20/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21682493 | 1.00 | PDE5A (0.83) | PDE5A | |
| SCHEMBL24402694 | 0.94 | PDE5A (0.81) | PDE5A | |
| Citric Acid SCHEMBL21682596 | 0.94 | PDE5A (0.73) | PDE5A | |
| SCHEMBL21682628 | 0.94 | PDE5A (0.84) | PDE5A | |
| SCHEMBL21705352 | 0.91 | PDE5A (0.68) | PDE5A | |
| SCHEMBL21705157 | 0.91 | PDE5A (0.83) | PDE5A | |
| SCHEMBL21682494 | 0.91 | PDE5A (0.83) | PDE5A | |
| SCHEMBL6500779 | 0.91 | PDE5A (0.82) | PDE5A | |
| SCHEMBL20567812 | 0.91 | PDE5A (1.00) | PDE5A | |
| SCHEMBL31651380 | 0.91 | PDE5A (1.00) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4236952-A1 | NO-PDE5 INHIBITOR FOR USE IN TREATING DRY AGE-RELATED MACULAR DEGENERATION, GEOGRAPHIC ATROPHY AND GLAUCOMA-ASSOCIATED NEURODEGENERATION | Nicox S.A. (FR) | 2023-09-06 | — | — | EP | claimed |
| WO-2022090379-A1 | NO-PDE5 INHIBITOR FOR USE IN TREATING DRY AGE-RELATED MACULAR DEGENERATION, GEOGRAPHIC ATROPHY AND GLAUCOMA-ASSOCIATED NEURODEGENERATION | NICOX S.A. (FR) | 2022-05-05 | — | — | WO | claimed |
| EP-4236952-A1 | NO-PDE5 INHIBITOR FOR USE IN TREATING DRY AGE-RELATED MACULAR DEGENERATION, GEOGRAPHIC ATROPHY AND GLAUCOMA-ASSOCIATED NEURODEGENERATION | Nicox S.A. (FR) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022090379-A1 | NO-PDE5 INHIBITOR FOR USE IN TREATING DRY AGE-RELATED MACULAR DEGENERATION, GEOGRAPHIC ATROPHY AND GLAUCOMA-ASSOCIATED NEURODEGENERATION | NICOX S.A. (FR) | 2022-05-05 | — | — | WO | disclosed |