SCHEMBL29601006

SCHEMBL29601006

Clc1ccc(-c2ccc3sc4ccccc4c3c2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.54
GPR3 P46089 1/20 0.52
CYP1A2 P05177 3/20 0.45
MAPT P10636 3/20 0.43
ALDH1A1 P00352 2/20 0.43
HPGD P15428 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
PIM3 Q86V86 1/20 0.40
GABRA1 P14867 1/20 0.40
GABRA5 P31644 1/20 0.40
ALOX5 P09917 2/20 0.38
LOXL2 Q9Y4K0 1/20 0.38
PTPN7 P35236 1/20 0.38
DUSP3 P51452 1/20 0.38
PTPN12 Q05209 1/20 0.38
PTPN22 Q9Y2R2 1/20 0.38
CYP1A1 P04798 1/20 0.38
CYP1B1 Q16678 1/20 0.38
LIMK1 P53667 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15850907 1.00 KDM4E (0.54) KDM4EGPR3CYP1A2MAPTALDH1A1
SCHEMBL10040873 1.00 KDM4E (0.54) KDM4EGPR3CYP1A2MAPTALDH1A1
SCHEMBL23314362 0.93 KDM4E (0.64) KDM4EGPR3CYP1A2MAPTALDH1A1
SCHEMBL27394289 0.91 KDM4E (0.62) KDM4EGPR3CYP1A2MAPTALDH1A1
SCHEMBL15850952 0.91 CYP1A2 (0.58) KDM4ECYP1A2ALDH1A1RAB9ASMN1; SMN2
SCHEMBL30563047 0.89 GPR3 (0.52) KDM4EGPR3CYP1A2MAPTALDH1A1
SCHEMBL23235920 0.89 GPR3 (0.52) KDM4EGPR3CYP1A2MAPTALDH1A1
SCHEMBL15836057 0.88 GPR3 (0.67) KDM4EGPR3CYP1A2MAPTALDH1A1
SCHEMBL20706794 0.88 GPR3 (0.67) KDM4EGPR3CYP1A2MAPTALDH1A1
SCHEMBL15836028 0.88 GPR3 (0.67) KDM4EGPR3CYP1A2MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114149461-B Organic compound and organic electroluminescent element comprising same 材料科学有限公司 2024-05-31 CN disclosed
CN-114149461-A Organic compound and organic electroluminescent element comprising same 材料科学有限公司 2022-03-08 CN disclosed