Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN1 | Q92952 | 1/20 | 0.44 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.44 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 9/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.41 |
| ▸ | NPC1 | O15118 | 9/20 | 0.41 |
| ▸ | RAB9A | P51151 | 8/20 | 0.41 |
| ▸ | LCK | P06239 | 4/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27039903 | 1.00 | KCNN1 (0.44) | KCNN1KCNN2KCNN3SLC2A1KDR | |
| SCHEMBL24358082 | 0.87 | KCNN1 (0.42) | KCNN1KCNN2KCNN3SLC2A1KDR | |
| SCHEMBL27039759 | 0.84 | KCNN1 (0.58) | KCNN1KCNN2KCNN3SLC2A1KDR | |
| SCHEMBL29601738 | 0.81 | DHODH (0.50) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL27039803 | 0.81 | DHODH (0.50) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL24358008 | 0.80 | KDR (0.54) | KCNN1KCNN2KCNN3SLC2A1KDR | |
| SCHEMBL30745731 | 0.80 | KDR (0.54) | KCNN1KCNN2KCNN3SLC2A1KDR | |
| SCHEMBL22599212 | 0.76 | KDR (0.48) | KCNN1KCNN2KCNN3SLC2A1KDR | |
| SCHEMBL30000215 | 0.76 | KDR (0.48) | KCNN1KCNN2KCNN3SLC2A1KDR | |
| SCHEMBL24357990 | 0.74 | KCNN1 (0.70) | KCNN1KCNN2KCNN3SLC2A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4232449-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | Celgene Corporation (US) | 2023-08-30 | — | — | EP | disclosed |
| WO-2022087326-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | CELGENE CORPORATION (US) | 2022-04-28 | — | — | WO | disclosed |