SCHEMBL29601295

SCHEMBL29601295

Oc1ccc(C2(c3ccc(O)cc3)c3ccc(-c4ccc5ccccc5c4)cc3-c3cc(-c4ccc5ccccc5c4)ccc32)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 9/20 0.61
ESR1 P03372 8/20 0.61
HSD17B1 P14061 3/20 0.49
HSD17B2 P37059 3/20 0.49
ALOX5 P09917 1/20 0.46
CYP1A2 P05177 2/20 0.44
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2B6 P20813 1/20 0.42
CYP2C19 P33261 1/20 0.42
HDAC4 P56524 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
MIF P14174 1/20 0.40
MEN1 O00255 1/20 0.40
NPC1 O15118 1/20 0.40
HSP90AA1 P07900 1/20 0.40
RAB9A P51151 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20796291 1.00 ESR2 (0.61) ESR2ESR1HSD17B1HSD17B2ALOX5
SCHEMBL22187658 0.91 ESR2 (0.53) ESR2ESR1HSD17B1HSD17B2ALOX5
SCHEMBL20795866 0.88 ESR2 (0.61) ESR2ESR1HSD17B1HSD17B2ALOX5
SCHEMBL29601900 0.88 ESR2 (0.61) ESR2ESR1HSD17B1HSD17B2ALOX5
SCHEMBL29601892 0.85 MMP3 (0.52) ESR2ESR1HSD17B1HSD17B2ALOX5
SCHEMBL2674735 0.85 MMP3 (0.52) ESR2ESR1HSD17B1HSD17B2ALOX5
SCHEMBL18184912 0.85 ESR2 (0.57) ESR2ESR1HSD17B1HSD17B2ALOX5
SCHEMBL18184908 0.84 ESR2 (0.53) ESR2ESR1HSD17B1HSD17B2ALOX5
SCHEMBL22187720 0.82 ESR2 (0.60) ESR2ESR1HSD17B1HSD17B2CYP1A2
SCHEMBL22187630 0.81 ESR2 (0.62) ESR2ESR1HSD17B1HSD17B2ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113474685-B optical lens 帝人株式会社 2024-05-28 CN disclosed
CN-113330051-B Thermoplastic resin and optical member 帝人株式会社 2023-04-28 CN disclosed
CN-110741030-B Thermoplastic resin and optical member 帝人株式会社 2022-06-17 CN disclosed
CN-114375313-A Thermoplastic resin and optical member comprising the same 帝人株式会社 2022-04-19 CN disclosed