Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 3/20 | 0.63 |
| ▸ | CNR1 | P21554 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.63 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | STK10 | O94804 | 1/20 | 0.38 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5484533 | 1.00 | GPR55 (0.63) | GPR55CNR1HTTGPR35CHRM2 | |
| SCHEMBL23983150 | 0.95 | CNR1 (0.58) | GPR55CNR1HTTGPR35CHRM2 | |
| SCHEMBL22111803 | 0.90 | CNR1 (0.53) | GPR55CNR1HTTGPR35CHRM2 | |
| SCHEMBL22076811 | 0.90 | CNR1 (0.56) | GPR55CNR1HTTGPR35CHRM2 | |
| SCHEMBL31003652 | 0.90 | CNR1 (0.53) | GPR55CNR1HTTGPR35CHRM2 | |
| SCHEMBL23791516 | 0.90 | CNR1 (0.56) | GPR55CNR1HTTGPR35CHRM2 | |
| SCHEMBL22076820 | 0.90 | CNR1 (0.53) | GPR55CNR1HTTGPR35CHRM2 | |
| SCHEMBL22111761 | 0.90 | CNR1 (0.53) | GPR55CNR1HTTGPR35CHRM2 | |
| SCHEMBL22111890 | 0.90 | CNR1 (0.56) | GPR55CNR1HTTGPR35CHRM2 | |
| SCHEMBL31185087 | 0.89 | CNR1 (0.55) | GPR55CNR1HTTGPR35CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230391721-A1 | ANTICANCER COMPOUNDS SELECTIVE FOR ER-POSITIVE CANCERS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2023-12-07 | — | — | US | disclosed |
| EP-4232038-A1 | ANTICANCER COMPOUNDS SELECTIVE FOR ER-POSITIVE CANCERS | The Board of Trustees of the University of Illinois (US) | 2023-08-30 | — | — | EP | disclosed |
| WO-2022087234-A1 | ANTICANCER COMPOUNDS SELECTIVE FOR ER-POSITIVE CANCERS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2022-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230391721-A1 | ANTICANCER COMPOUNDS SELECTIVE FOR ER-POSITIVE CANCERS | ESR1, ESR2, ESRRG | GPR55 1088/4885CNR1 2217/4885HTT 3298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.