SCHEMBL29601376

SCHEMBL29601376

OCCOc1cc2c(-c3ccc4ccccc4c3)cccc2c(-c2cccc3c(-c4ccc5ccccc5c4)cccc23)c1OCCO

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.40
HDAC4 P56524 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
CHRNB4 P30926 1/20 0.37
CHRNA3 P32297 1/20 0.37
CHRNA7 P36544 1/20 0.37
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36
HTR1D P28221 1/20 0.36
HTR1B P28222 1/20 0.36
GPR84 Q9NQS5 1/20 0.36
ALOX5AP P20292 2/20 0.35
FEN1 P39748 2/20 0.35
S1PR4 O95977 2/20 0.35
S1PR5 Q9H228 2/20 0.35
CNR2 P34972 4/20 0.35
CNR1 P21554 2/20 0.35
ALOX5 P09917 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29601891 0.87 HTR1B (0.42) IDO1CHRNB4CHRNA3CHRNA7HTR1D
SCHEMBL29601857 0.87 IDO1 (0.42) IDO1
SCHEMBL29127416 0.86 IDO1 (0.46) IDO1HDAC4HDAC2HDAC8CHRNB4
SCHEMBL27113964 0.86 IDO1 (0.48) IDO1HDAC4HDAC2HDAC8CHRNB4
SCHEMBL30822053 0.85 HTR1B (0.40) IDO1HTR1DHTR1BCNR2CNR1
SCHEMBL29601565 0.85 HDAC4 (0.39) IDO1HDAC4HDAC2HDAC8CHRNB4
SCHEMBL29601896 0.84 IDO1 (0.36) IDO1HDAC4HDAC2HDAC8CHRNB4
SCHEMBL29601474 0.84 IDO1 (0.36) IDO1HDAC4HDAC2HDAC8CHRNB4
SCHEMBL29601571 0.84 CHRNB4 (0.39) IDO1HDAC8CHRNB4CHRNA3CHRNA7
SCHEMBL27113965 0.82 IDO1 (0.47) IDO1HDAC4HDAC2HDAC8SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113474321-B Compound having binaphthyl skeleton and method for producing compound having binaphthyl skeleton 帝人株式会社 2023-12-15 CN disclosed
CN-113330051-B Thermoplastic resin and optical member 帝人株式会社 2023-04-28 CN disclosed
CN-114375313-A Thermoplastic resin and optical member comprising the same 帝人株式会社 2022-04-19 CN disclosed