SCHEMBL29601896

SCHEMBL29601896

OCCOc1cc2ccc(-c3ccc4ccccc4c3)cc2c(-c2cccc3ccc(-c4ccc5ccccc5c4)cc23)c1OCCO

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.36
HSD17B1 P14061 2/20 0.35
HSD17B2 P37059 2/20 0.35
SLC6A9 P48067 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HTR1D P28221 1/20 0.35
HTR1B P28222 1/20 0.35
CNR2 P34972 3/20 0.34
CNR1 P21554 2/20 0.34
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
CHRNB4 P30926 2/20 0.34
CHRNA3 P32297 2/20 0.34
CHRNA7 P36544 2/20 0.34
TNF P01375 1/20 0.34
MCL1 Q07820 2/20 0.33
SGK1 O00141 1/20 0.33
ALOX5 P09917 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29601600 0.93 SLC6A9 (0.42) IDO1HSD17B1HSD17B2SLC6A9HTR1D
SCHEMBL29601474 0.91 IDO1 (0.36) IDO1HSD17B1HSD17B2SLC6A9HDAC4
SCHEMBL29127414 0.88 IDO1 (0.42) IDO1HSD17B1HSD17B2SLC6A9HDAC4
SCHEMBL29351066 0.85 HTR1B (0.43) IDO1SLC6A9HTR1DHTR1BCNR2
SCHEMBL11331409 0.85 HTR1B (0.43) IDO1SLC6A9HTR1DHTR1BCNR2
SCHEMBL29601376 0.84 IDO1 (0.40) IDO1HDAC4HDAC2HDAC8HTR1D
SCHEMBL29601612 0.83 SLC6A9 (0.42) HSD17B1HSD17B2SLC6A9ESR1ESR2
SCHEMBL29601571 0.83 CHRNB4 (0.39) IDO1SLC6A9HDAC8HTR1DHTR1B
SCHEMBL30675906 0.82 IDO1 (0.49) IDO1HSD17B1HSD17B2SLC6A9HDAC4
SCHEMBL28350551 0.80 SLC6A9 (0.47) IDO1SLC6A9HTR1DHTR1BCNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114375313-A Thermoplastic resin and optical member comprising the same 帝人株式会社 2022-04-19 CN disclosed