Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 19/20 | 0.59 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arginine SCHEMBL28724004 | 1.00 | HCAR2 (0.59) | HCAR2CYP2C8CYP2C9 | |
| Lysine SCHEMBL28724514 | 0.85 | HCAR2 (0.65) | HCAR2CYP2C8CYP2C9 | |
| Lysine SCHEMBL29600875 | 0.85 | HCAR2 (0.65) | HCAR2CYP2C8CYP2C9 | |
| SCHEMBL28724001 | 0.85 | HCAR2 (0.47) | HCAR2CYP2C8CYP2C9 | |
| Guanidine SCHEMBL29186810 | 0.82 | HCAR2 (0.81) | HCAR2CYP2C8CYP2C9 | |
| Arginine SCHEMBL1661219 | 0.81 | GRIA1 (0.46) | — | |
| Arginine SCHEMBL1663172 | 0.81 | GRIA1 (0.46) | — | |
| SCHEMBL14250016 | 0.79 | CYP2C9 (0.46) | HCAR2CYP2C9 | |
| Arginine SCHEMBL26914670 | 0.79 | KIF11 (0.46) | — | |
| SCHEMBL29403073 | 0.79 | HCAR2 (0.92) | HCAR2CYP2C8CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114369040-B | 2- (3- (p-hydroxyphenyl) -propionamido) -benzoic acid glucosamine salt and preparation method thereof | 广州同隽医药科技有限公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-114369040-A | 2- (3- (p-hydroxyphenyl) -propionamido) -benzoic acid glucosamine salt and preparation method thereof | 广州同隽医药科技有限公司 | 2022-04-19 | — | — | CN | disclosed |