Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327356 | 1.00 | FGFR3 (0.48) | FGFR3KDRHRH4ADORA2AADORA1 | |
| SCHEMBL25458389 | 0.86 | KDR (0.50) | FGFR3KDRHRH4KCNH2CHEK1 | |
| SCHEMBL30085870 | 0.86 | KDR (0.50) | FGFR3KDRHRH4KCNH2CHEK1 | |
| SCHEMBL30085837 | 0.83 | FGFR3 (0.48) | FGFR3KDRHRH4KCNH2CHEK1 | |
| SCHEMBL25458392 | 0.83 | FGFR3 (0.48) | FGFR3KDRHRH4KCNH2CHEK1 | |
| SCHEMBL14656027 | 0.82 | PIK3CD (0.45) | FGFR3KDRCHEK1PIK3CDPIK3CA | |
| SCHEMBL25459484 | 0.81 | ADORA3 (0.48) | FGFR3KDRKCNH2CHEK1FLT3 | |
| SCHEMBL29020125 | 0.79 | CHEK1 (0.53) | FGFR3KDRCHEK1MKNK1MKNK2 | |
| SCHEMBL28761423 | 0.78 | FGFR3 (0.46) | FGFR3KDRHRH4KCNH2CHEK1 | |
| SCHEMBL30085456 | 0.78 | HRH4 (0.64) | HRH4PIK3CAHTR6HRH3LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114369097-B | Heteroaromatic AhR inhibitors | 山东轩竹医药科技有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-114369097-A | Heteroaromatic AhR inhibitors | 山东轩竹医药科技有限公司 | 2022-04-19 | — | — | CN | disclosed |