Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 6/20 | 0.35 |
| ▸ | RXRB | P28702 | 5/20 | 0.35 |
| ▸ | RXRG | P48443 | 5/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24359494 | 0.99 | EGFR (0.39) | EGFRRXRARXRBRXRGCYP1A2 | |
| SCHEMBL13376117 | 0.83 | EGFR (0.38) | EGFR | |
| SCHEMBL26081392 | 0.82 | RXRA (0.37) | EGFRRXRARXRBRXRGCYP1A2 | |
| SCHEMBL14466207 | 0.82 | EGFR (0.40) | EGFR | |
| SCHEMBL22356571 | 0.81 | MAPK1 (0.38) | EGFRRXRARXRBRXRGRARA | |
| SCHEMBL22320162 | 0.81 | RXRA (0.36) | EGFRRXRARXRBRXRGCYP1A2 | |
| SCHEMBL15590936 | 0.78 | EGFR (0.39) | EGFR | |
| SCHEMBL30503395 | 0.78 | CYP1A2 (0.36) | RXRARXRBCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL13818637 | 0.77 | TSHR (0.35) | RXRACYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL29605279 | 0.76 | EGFR (0.36) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4232484-A1 | MULTIDENTATE LEWIS BASE CATALYSTS AND METHODS FOR USE THEREOF | ExxonMobil Chemical Patents Inc. (US) | 2023-08-30 | — | — | EP | disclosed |
| WO-2022087121-A1 | MULTIDENTATE LEWIS BASE CATALYSTS AND METHODS FOR USE THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2022-04-28 | — | — | WO | disclosed |