SCHEMBL29601554

SCHEMBL29601554

O=C1CCC(N2C(=O)c3cccc([N+](=O)[O-])c3C2=O)C(=O)N1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 17/20 1.00
CRBN Q96SW2 17/20 1.00
IKZF3 Q9UKT9 2/20 0.68
TNF P01375 1/20 0.68
IL1B P01584 1/20 0.68
TBXA2R P21731 1/20 0.68
IKZF1 Q13422 1/20 0.68
ALDH1A1 P00352 1/20 0.65
CHRM2 P08172 1/20 0.65
OPRM1 P35372 1/20 0.65
CYP1A2 P05177 1/20 0.65
TSHR P16473 1/20 0.65
TDP1 Q9NUW8 1/20 0.65
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15930069 1.00 DDB1 (1.00) DDB1CRBNIKZF3TNFIL1B
SCHEMBL2110965 1.00 DDB1 (1.00) DDB1CRBNIKZF3TNFIL1B
SCHEMBL1398974 1.00 DDB1 (1.00) DDB1CRBNIKZF3TNFIL1B
SCHEMBL1096288 1.00 DDB1 (1.00) DDB1CRBNIKZF3TNFIL1B
SCHEMBL15930063 1.00 DDB1 (1.00) DDB1CRBNIKZF3TNFIL1B
SCHEMBL19611941 0.93 DDB1 (0.87) DDB1CRBNIKZF3TNFIL1B
SCHEMBL18263911 0.93 DDB1 (0.87) DDB1CRBNIKZF3TNFIL1B
SCHEMBL18263926 0.93 DDB1 (0.87) DDB1CRBNIKZF3TNFIL1B
SCHEMBL19359185 0.90 DDB1 (0.82) DDB1CRBNIKZF3TNFIL1B
SCHEMBL29923364 0.90 DDB1 (0.82) DDB1CRBNIKZF3TNFIL1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115557936-B Preparation method and application of pomalidomide derivative serving as feed additive 河南湾流生物科技有限公司 2024-12-06 CN claimed
CN-109678840-B Preparation method of pomalidomide 河北菲尼斯生物技术有限公司 2023-12-01 CN claimed
CN-115572283-A Pomalidomide feed additive and preparation method and application thereof 河南湾流生物科技有限公司 2023-01-06 CN claimed
CN-115557936-A Preparation method and application of pomalidomide derivative capable of being used as feed additive 河南湾流生物科技有限公司 2023-01-03 CN claimed
CN-114605381-A Preparation method of pomalidomide 南京海辰药业股份有限公司 2022-06-10 CN claimed
CN-121574723-A Application of pomalidomide and various derivatives thereof as electrochemiluminescence probes 厦门医学院 2026-02-27 CN disclosed
WO-2024256569-A1 NOVEL CDK DEGRADERS RIJKSUNIVERSITEIT GRONINGEN (NL) 2024-12-19 WO disclosed
CN-115572283-B Pomalidomide feed additive and preparation method and application thereof 合肥市贵谦信息科技有限公司 2024-12-17 CN disclosed
CN-115572283-B Pomalidomide feed additive and preparation method and application thereof 合肥市贵谦信息科技有限公司 2024-12-17 CN disclosed
CN-115557936-B Preparation method and application of pomalidomide derivative serving as feed additive 河南湾流生物科技有限公司 2024-12-06 CN disclosed
CN-112771038-B Pyridazine derivatives as SMARCA2/4 degrading agents 奥里吉恩发现科技有限公司 2024-09-24 CN disclosed
WO-2024178067-A1 CHIMERIC DEGRADERS OF CYCLIN-DEPENDENT KINASE 9 AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2024-08-29 WO disclosed
CN-113214220-B Substituted 4-aminoisoindoline-1, 3-dione compounds and their use for the treatment of lymphomas 细胞基因公司 2024-04-02 CN disclosed
CN-109678840-B Preparation method of pomalidomide 河北菲尼斯生物技术有限公司 2023-12-01 CN disclosed
CN-115572283-A Pomalidomide feed additive and preparation method and application thereof 河南湾流生物科技有限公司 2023-01-06 CN disclosed
CN-115557936-A Preparation method and application of pomalidomide derivative capable of being used as feed additive 河南湾流生物科技有限公司 2023-01-03 CN disclosed
CN-108350062-B Targeted protein degradation to attenuate adverse inflammatory responses associated with adoptive T cell therapy 达纳-法伯癌症研究所股份有限公司 2022-10-14 CN disclosed
CN-114907314-A Chemical synthesis method of pomalidomide 浙江工业大学 2022-08-16 CN disclosed
CN-114605381-A Preparation method of pomalidomide 南京海辰药业股份有限公司 2022-06-10 CN disclosed
CN-114605381-A Preparation method of pomalidomide 南京海辰药业股份有限公司 2022-06-10 CN disclosed