Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 15/20 | 0.82 |
| ▸ | CRBN | Q96SW2 | 15/20 | 0.82 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.54 |
| ▸ | TNF | P01375 | 1/20 | 0.54 |
| ▸ | IL1B | P01584 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.54 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19359185 | 1.00 | DDB1 (0.82) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL19359187 | 1.00 | DDB1 (0.82) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL18263911 | 0.91 | DDB1 (0.87) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL19611941 | 0.91 | DDB1 (0.87) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL18263926 | 0.91 | DDB1 (0.87) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL2110965 | 0.90 | DDB1 (1.00) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL29601554 | 0.90 | DDB1 (1.00) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL1096288 | 0.90 | DDB1 (1.00) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL15930063 | 0.90 | DDB1 (1.00) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL15930069 | 0.90 | DDB1 (1.00) | DDB1CRBNIKZF3TNFIL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153644-B | Small molecules against CEREBLON to enhance effector T cell function | H·李·莫菲特癌症中心研究有限公司 | 2022-10-21 | — | — | CN | disclosed |