Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29601899 | 0.94 | HSP90AA1 (0.33) | HSP90AA1NPC1ALDH1A1PLA2G1BNFKB1 | |
| SCHEMBL29601171 | 0.92 | NPC1 (0.34) | HSP90AA1NPC1ALDH1A1PLA2G1BNFKB1 | |
| SCHEMBL29601888 | 0.91 | HSP90AA1 (0.33) | HSP90AA1NPC1ALDH1A1PLA2G1BNFKB1 | |
| SCHEMBL24359601 | 0.79 | HSP90AA1 (0.50) | HSP90AA1NPC1ALDH1A1PLA2G1BNFKB1 | |
| SCHEMBL30619633 | 0.73 | CNR1 (0.31) | ALDH1A1 | |
| SCHEMBL24359571 | 0.72 | HSP90AA1 (0.44) | HSP90AA1NPC1RAB9AL3MBTL1 | |
| SCHEMBL18890281 | 0.70 | HSP90AA1 (0.56) | HSP90AA1ALDH1A1 | |
| SCHEMBL30288311 | 0.70 | NPC1 (0.32) | NPC1RAB9A | |
| SCHEMBL30619642 | 0.69 | NPC1 (0.31) | NPC1RAB9A | |
| SCHEMBL6316054 | 0.68 | TSHR (0.38) | HSP90AA1NPC1ALDH1A1PLA2G1BNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230312772-A1 | Multidentate Lewis Base Catalysts and Methods for use Thereof | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2023-10-05 | — | — | US | disclosed |
| EP-4232484-A1 | MULTIDENTATE LEWIS BASE CATALYSTS AND METHODS FOR USE THEREOF | ExxonMobil Chemical Patents Inc. (US) | 2023-08-30 | — | — | EP | disclosed |
| WO-2022087121-A1 | MULTIDENTATE LEWIS BASE CATALYSTS AND METHODS FOR USE THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2022-04-28 | — | — | WO | disclosed |